Effect of Stereochemical Configuration on the Transport and Metabolism of Catechins from Green Tea across Caco-2 Monolayers

Effect of Stereochemical Configuration on the Transport and Metabolism of Catechins from Green Tea across Caco-2 Monolayers

The transcellular transport and metabolism of eight green tea catechins (GTCs) were studied in Caco-2 monolayers, with the aim of investigating the effect of cis–trans isomerism on the membrane permeability and biotransformation of GTCs. The results showed that the catechin stereochemistry...

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Bibliographic Details
Main Authors: Zeyi Ai, Shuyuan Liu, Fengfeng Qu, Haojie Zhang, Yuqiong Chen, Dejiang Ni
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:Molecules
Subjects:
stereochemical configuration
cis–trans catechins
bidirectional transport
efflux pumps
metabolism
Online Access:https://www.mdpi.com/1420-3049/24/6/1185

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