Tackling HLA Deficiencies Head on with Oncolytic Viruses

Tackling HLA Deficiencies Head on with Oncolytic Viruses

Dysregulation of HLA (human leukocyte antigen) function is increasingly recognized as a common escape mechanism for cancers subject to the pressures exerted by immunosurveillance or immunotherapeutic interventions. Oncolytic viruses have the potential to counter this resistance by upregulating HLA e...

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Bibliographic Details
Main Authors: Kerry Fisher, Ahmet Hazini, Leonard W. Seymour
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Cancers
Subjects:
oncolytic virus
class I HLA
immunosurveillance
immunotherapy
Online Access:https://www.mdpi.com/2072-6694/13/4/719

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