Kinetic Ultrasound-Assisted Extraction as a Sustainable Approach for the Recovery of Phenolics Accumulated through UVA Treatment in Strawberry By-Products
Ultrasound-assisted extraction (UAE) is an efficient and sustainable method for extracting bioactive compounds from agro-industrial by-products. Moreover, it has been reported that ultraviolet A (UVA) radiation can induce the biosynthesis and accumulation of bioactive phenolic compounds. This study...
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| Format: | Article |
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MDPI AG
2023-08-01
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| Series: | Foods |
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| Online Access: | https://www.mdpi.com/2304-8158/12/16/2989 |
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| author | Esteban Villamil-Galindo Alejandro Gastélum-Estrada Cristina Chuck-Hernandez Marilena Antunes-Ricardo Edwin E. Reza-Zaldivar Andrea Piagentini Daniel A. Jacobo-Velázquez |
| author_facet | Esteban Villamil-Galindo Alejandro Gastélum-Estrada Cristina Chuck-Hernandez Marilena Antunes-Ricardo Edwin E. Reza-Zaldivar Andrea Piagentini Daniel A. Jacobo-Velázquez |
| author_sort | Esteban Villamil-Galindo |
| collection | DOAJ |
| description | Ultrasound-assisted extraction (UAE) is an efficient and sustainable method for extracting bioactive compounds from agro-industrial by-products. Moreover, it has been reported that ultraviolet A (UVA) radiation can induce the biosynthesis and accumulation of bioactive phenolic compounds. This study optimized the efficiency of ultrasound-assisted extraction (UAE) for recovering ultraviolet A (UVA)-induced phenolic compounds in strawberry by-products (RF-N). The impact of three factors (solid-liquid ratio, ethanol concentration, and ultrasound power) on total phenolic compound (TPC) kinetics using Peleg’s model was investigated. The developed model showed a suitable fit for both RF-N and strawberry by-products treated with UVA (RF-E). The optimal UAE conditions obtained were of a 1:30 ratio, 46% ethanol, and 100% ultrasound power, resulting in an average yield of 13 g total phenolics kg<sup>−1</sup>. The bioaccessibility of phenolic compounds during in-vitro digestion was 36.5%, with agrimoniin being the predominant compound. UAE combined with UVA treatment increased the bioactivity of RF extracts, displaying significant anti-proliferative effects on HT29 and Caco-2 cancer cell lines, as well as anti-inflammatory potential and cellular antioxidant activity. The ultrasound proved to be a sustainable and effective technique for extracting phenolic compounds from RF, contributing to the valorization of strawberry agro-industrial by-products, and maximizing their nutraceutical potential. |
| first_indexed | 2024-03-10T23:57:36Z |
| format | Article |
| id | doaj.art-b71e680ac5024a998a9eda55f2343756 |
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| issn | 2304-8158 |
| language | English |
| last_indexed | 2024-03-10T23:57:36Z |
| publishDate | 2023-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Foods |
| spelling | doaj.art-b71e680ac5024a998a9eda55f23437562023-11-19T01:05:01ZengMDPI AGFoods2304-81582023-08-011216298910.3390/foods12162989Kinetic Ultrasound-Assisted Extraction as a Sustainable Approach for the Recovery of Phenolics Accumulated through UVA Treatment in Strawberry By-ProductsEsteban Villamil-Galindo0Alejandro Gastélum-Estrada1Cristina Chuck-Hernandez2Marilena Antunes-Ricardo3Edwin E. Reza-Zaldivar4Andrea Piagentini5Daniel A. Jacobo-Velázquez6Instituto de Tecnología de Alimentos, Facultad de Ingeniería Química, Universidad Nacional del Litoral, Santiago del Estero 2829, Santa Fe 3000, ArgentinaTecnológico de Monterrey, Institute for Obesity Research, Av. Eugenio Garza Sada 2501, Monterrey 64849, MexicoTecnológico de Monterrey, Institute for Obesity Research, Av. Eugenio Garza Sada 2501, Monterrey 64849, MexicoTecnológico de Monterrey, Institute for Obesity Research, Av. Eugenio Garza Sada 2501, Monterrey 64849, MexicoTecnológico de Monterrey, Institute for Obesity Research, Av. Eugenio Garza Sada 2501, Monterrey 64849, MexicoInstituto de Tecnología de Alimentos, Facultad de Ingeniería Química, Universidad Nacional del Litoral, Santiago del Estero 2829, Santa Fe 3000, ArgentinaTecnológico de Monterrey, Institute for Obesity Research, Av. Eugenio Garza Sada 2501, Monterrey 64849, MexicoUltrasound-assisted extraction (UAE) is an efficient and sustainable method for extracting bioactive compounds from agro-industrial by-products. Moreover, it has been reported that ultraviolet A (UVA) radiation can induce the biosynthesis and accumulation of bioactive phenolic compounds. This study optimized the efficiency of ultrasound-assisted extraction (UAE) for recovering ultraviolet A (UVA)-induced phenolic compounds in strawberry by-products (RF-N). The impact of three factors (solid-liquid ratio, ethanol concentration, and ultrasound power) on total phenolic compound (TPC) kinetics using Peleg’s model was investigated. The developed model showed a suitable fit for both RF-N and strawberry by-products treated with UVA (RF-E). The optimal UAE conditions obtained were of a 1:30 ratio, 46% ethanol, and 100% ultrasound power, resulting in an average yield of 13 g total phenolics kg<sup>−1</sup>. The bioaccessibility of phenolic compounds during in-vitro digestion was 36.5%, with agrimoniin being the predominant compound. UAE combined with UVA treatment increased the bioactivity of RF extracts, displaying significant anti-proliferative effects on HT29 and Caco-2 cancer cell lines, as well as anti-inflammatory potential and cellular antioxidant activity. The ultrasound proved to be a sustainable and effective technique for extracting phenolic compounds from RF, contributing to the valorization of strawberry agro-industrial by-products, and maximizing their nutraceutical potential.https://www.mdpi.com/2304-8158/12/16/2989bioactive compoundsgreen extractionnutraceutical potentialPeleg’s modelellagitannins |
| spellingShingle | Esteban Villamil-Galindo Alejandro Gastélum-Estrada Cristina Chuck-Hernandez Marilena Antunes-Ricardo Edwin E. Reza-Zaldivar Andrea Piagentini Daniel A. Jacobo-Velázquez Kinetic Ultrasound-Assisted Extraction as a Sustainable Approach for the Recovery of Phenolics Accumulated through UVA Treatment in Strawberry By-Products Foods bioactive compounds green extraction nutraceutical potential Peleg’s model ellagitannins |
| title | Kinetic Ultrasound-Assisted Extraction as a Sustainable Approach for the Recovery of Phenolics Accumulated through UVA Treatment in Strawberry By-Products |
| title_full | Kinetic Ultrasound-Assisted Extraction as a Sustainable Approach for the Recovery of Phenolics Accumulated through UVA Treatment in Strawberry By-Products |
| title_fullStr | Kinetic Ultrasound-Assisted Extraction as a Sustainable Approach for the Recovery of Phenolics Accumulated through UVA Treatment in Strawberry By-Products |
| title_full_unstemmed | Kinetic Ultrasound-Assisted Extraction as a Sustainable Approach for the Recovery of Phenolics Accumulated through UVA Treatment in Strawberry By-Products |
| title_short | Kinetic Ultrasound-Assisted Extraction as a Sustainable Approach for the Recovery of Phenolics Accumulated through UVA Treatment in Strawberry By-Products |
| title_sort | kinetic ultrasound assisted extraction as a sustainable approach for the recovery of phenolics accumulated through uva treatment in strawberry by products |
| topic | bioactive compounds green extraction nutraceutical potential Peleg’s model ellagitannins |
| url | https://www.mdpi.com/2304-8158/12/16/2989 |
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