The novel sigma-2 receptor ligand SW43 stabilizes pancreas cancer progression in combination with gemcitabine

<p>Abstract</p> <p>Background</p> <p>Sigma-2 receptors are over-expressed in proliferating cancer cells, making an attractive target for the targeted treatment of pancreatic cancer. In this study, we investigated the role of the novel sigma-2 receptor ligand SW43 to ind...

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Bibliographic Details
Main Authors: Goedegebuure Peter, Spitzer Dirk, Mitchem Jonathan B, Tu Zhude, Vangveravong Suwanna, Xu Jinbin, Hornick John R, Mach Robert H, Hawkins William G
Format: Article
Language:English
Published: BMC 2010-11-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/9/1/298