Perfusion imaging heterogeneity during NO inhalation distinguishes pulmonary arterial hypertension (PAH) from healthy subjects and has potential as an imaging biomarker

Perfusion imaging heterogeneity during NO inhalation distinguishes pulmonary arterial hypertension (PAH) from healthy subjects and has potential as an imaging biomarker

Abstract Background Without aggressive treatment, pulmonary arterial hypertension (PAH) has a 5-year mortality of approximately 40%. A patient’s response to vasodilators at diagnosis impacts the therapeutic options and prognosis. We hypothesized that analyzing perfusion images acquired before and du...

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Bibliographic Details
Main Authors: Tilo Winkler, Puja Kohli, Vanessa J. Kelly, Ekaterina G. Kehl, Alison S. Witkin, Josanna M. Rodriguez-Lopez, Kathryn A. Hibbert, Mamary T. Kone, David M. Systrom, Aaron B. Waxman, Jose G. Venegas, Richard N. Channick, R. Scott Harris
Format: Article
Language:English
Published: BMC 2022-12-01
Series:Respiratory Research
Subjects:
Pulmonary circulation
Vascular physiology
Functional imaging
Positron emission tomography
Perfusion distribution
Ventilation
Online Access:https://doi.org/10.1186/s12931-022-02239-8

Internet

https://doi.org/10.1186/s12931-022-02239-8

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