Genome-wide transcriptome study using deep RNA sequencing for myocardial infarction and coronary artery calcification

Genome-wide transcriptome study using deep RNA sequencing for myocardial infarction and coronary artery calcification

Abstract Background Coronary artery calcification (CAC) is a noninvasive measure of coronary atherosclerosis, the proximal pathophysiology underlying most cases of myocardial infarction (MI). We sought to identify expression signatures of early MI and subclinical atherosclerosis in the Framingham He...

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Bibliographic Details
Main Authors: Xiaoling Zhang, Jeroen G. J. van Rooij, Yoshiyuki Wakabayashi, Shih-Jen Hwang, Yanqin Yang, Mohsen Ghanbari, Daniel Bos, BIOS Consortium, Daniel Levy, Andrew D. Johnson, Joyce B. J. van Meurs, Maryam Kavousi, Jun Zhu, Christopher J. O’Donnell
Format: Article
Language:English
Published: BMC 2021-02-01
Series:BMC Medical Genomics
Subjects:
Gene expression signatures
Protein-coding gene
Long intergenic non-coding RNA
Myocardial infarction
Coronary artery calcification
Whole blood
Online Access:https://doi.org/10.1186/s12920-020-00838-2

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