NIR responsive nanoenzymes via photothermal ablation and hypoxia reversal to potentiate the STING-dependent innate antitumor immunity

NIR responsive nanoenzymes via photothermal ablation and hypoxia reversal to potentiate the STING-dependent innate antitumor immunity

Despite advances in combined photothermal/immunotherapy of tumor, the therapeutic effect has been impaired due to hypoxic microenvironment and inadequate immune activation. Manganese ions directly activated the stimulator of interferon genes (STING) pathway and induced innate antitumor immunity. Her...

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Bibliographic Details
Main Authors: Qianzhe Li, Mengyu Yang, Xin Sun, Qinxin Wang, Beibei Yu, Aihua Gong, Miaomiao Zhang, Fengyi Du
Format: Article
Language:English
Published: Elsevier 2023-04-01
Series:Materials Today Bio
Subjects:
Prussian blue
Photothermal therapy
Nanoenzyme
Hypoxic reversal
cGAS-STING
Online Access:http://www.sciencedirect.com/science/article/pii/S2590006423000261

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