Reducing intraventricular hemorrhage following the implementation of a prevention bundle for neonatal hypothermia.
<h4>Introduction</h4>In very low birth weight (VLBW) infants, hypothermia immediately following birth is common even in countries rich in medical resources. The purpose of this study is to design a standard prevention bundle that decreases the rate of hypothermia among infants after birt...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2022-01-01
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| Series: | PLoS ONE |
| Online Access: | https://doi.org/10.1371/journal.pone.0273946 |
| _version_ | 1811258430258675712 |
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| author | Wei-Tse Chiu Yi-Hsuan Lu Yin-Ting Chen Yin Ling Tan Yi-Chieh Lin Yu-Lien Chen Hung-Chieh Chou Chien-Yi Chen Ting-An Yen Po-Nien Tsao |
| author_facet | Wei-Tse Chiu Yi-Hsuan Lu Yin-Ting Chen Yin Ling Tan Yi-Chieh Lin Yu-Lien Chen Hung-Chieh Chou Chien-Yi Chen Ting-An Yen Po-Nien Tsao |
| author_sort | Wei-Tse Chiu |
| collection | DOAJ |
| description | <h4>Introduction</h4>In very low birth weight (VLBW) infants, hypothermia immediately following birth is common even in countries rich in medical resources. The purpose of this study is to design a standard prevention bundle that decreases the rate of hypothermia among infants after birth and to investigate efficacy of the bundle and short-term outcomes for VLBW infants.<h4>Methods</h4>This quality improvement project was conducted from February 2017 to July 2018 on all VLBW preterm infants admitted at a single referral level III neonatal intensive care unit. The infants were classified into the pre-intervention (February to September 2017) and post-intervention (October 2017 to July 2018) groups according to the time periods when they were recruited. During the pre-intervention period, we analyzed the primary causes of hypothermia, developed solutions corresponding to each cause, integrated all solutions into a prevention bundle, and applied the bundle during the post-intervention period. Afterwards, the incidence of neonatal hypothermia and short-term outcomes, such as intraventricular hemorrhage (IVH), acidosis, and shock requiring inotropic agents, in each group were compared.<h4>Results</h4>A total of 95 VLBW infants were enrolled in the study, including 37 pre-intervention, and 58 post-intervention cases. The incidence of hypothermia in preterm infants decreased significantly upon the implementation of our prevention bundle, both in the delivery room (from 45.9% to 8.6%) and on admission (59.5% to 15.5%). In addition, the short-term outcomes of VLBW infants improved significantly, especially with the decreased incidence of IVH (from 21.6% to 5.2%, P = 0.015).<h4>Conclusions</h4>Our standardized prevention bundle for preventing hypothermia in VLBW infants is effective and decreased the IVH rate in VLBW infants. We strongly believe that this prevention bundle is a simple, low-cost, replicable, and effective tool that hospitals can adopt to improve VLBW infant outcomes. |
| first_indexed | 2024-04-12T18:14:15Z |
| format | Article |
| id | doaj.art-b7238ed96acf4a7bb48d69622947790e |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-04-12T18:14:15Z |
| publishDate | 2022-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-b7238ed96acf4a7bb48d69622947790e2022-12-22T03:21:43ZengPublic Library of Science (PLoS)PLoS ONE1932-62032022-01-01179e027394610.1371/journal.pone.0273946Reducing intraventricular hemorrhage following the implementation of a prevention bundle for neonatal hypothermia.Wei-Tse ChiuYi-Hsuan LuYin-Ting ChenYin Ling TanYi-Chieh LinYu-Lien ChenHung-Chieh ChouChien-Yi ChenTing-An YenPo-Nien Tsao<h4>Introduction</h4>In very low birth weight (VLBW) infants, hypothermia immediately following birth is common even in countries rich in medical resources. The purpose of this study is to design a standard prevention bundle that decreases the rate of hypothermia among infants after birth and to investigate efficacy of the bundle and short-term outcomes for VLBW infants.<h4>Methods</h4>This quality improvement project was conducted from February 2017 to July 2018 on all VLBW preterm infants admitted at a single referral level III neonatal intensive care unit. The infants were classified into the pre-intervention (February to September 2017) and post-intervention (October 2017 to July 2018) groups according to the time periods when they were recruited. During the pre-intervention period, we analyzed the primary causes of hypothermia, developed solutions corresponding to each cause, integrated all solutions into a prevention bundle, and applied the bundle during the post-intervention period. Afterwards, the incidence of neonatal hypothermia and short-term outcomes, such as intraventricular hemorrhage (IVH), acidosis, and shock requiring inotropic agents, in each group were compared.<h4>Results</h4>A total of 95 VLBW infants were enrolled in the study, including 37 pre-intervention, and 58 post-intervention cases. The incidence of hypothermia in preterm infants decreased significantly upon the implementation of our prevention bundle, both in the delivery room (from 45.9% to 8.6%) and on admission (59.5% to 15.5%). In addition, the short-term outcomes of VLBW infants improved significantly, especially with the decreased incidence of IVH (from 21.6% to 5.2%, P = 0.015).<h4>Conclusions</h4>Our standardized prevention bundle for preventing hypothermia in VLBW infants is effective and decreased the IVH rate in VLBW infants. We strongly believe that this prevention bundle is a simple, low-cost, replicable, and effective tool that hospitals can adopt to improve VLBW infant outcomes.https://doi.org/10.1371/journal.pone.0273946 |
| spellingShingle | Wei-Tse Chiu Yi-Hsuan Lu Yin-Ting Chen Yin Ling Tan Yi-Chieh Lin Yu-Lien Chen Hung-Chieh Chou Chien-Yi Chen Ting-An Yen Po-Nien Tsao Reducing intraventricular hemorrhage following the implementation of a prevention bundle for neonatal hypothermia. PLoS ONE |
| title | Reducing intraventricular hemorrhage following the implementation of a prevention bundle for neonatal hypothermia. |
| title_full | Reducing intraventricular hemorrhage following the implementation of a prevention bundle for neonatal hypothermia. |
| title_fullStr | Reducing intraventricular hemorrhage following the implementation of a prevention bundle for neonatal hypothermia. |
| title_full_unstemmed | Reducing intraventricular hemorrhage following the implementation of a prevention bundle for neonatal hypothermia. |
| title_short | Reducing intraventricular hemorrhage following the implementation of a prevention bundle for neonatal hypothermia. |
| title_sort | reducing intraventricular hemorrhage following the implementation of a prevention bundle for neonatal hypothermia |
| url | https://doi.org/10.1371/journal.pone.0273946 |
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