Growth factors that drive aggrecan synthesis in healthy articular cartilage. Role for transforming growth factor-β?

Growth factors that drive aggrecan synthesis in healthy articular cartilage. Role for transforming growth factor-β?

Introduction: Articular cartilage makes smooth movement possible and destruction of this tissue leads to loss of joint function. An important biomolecule that determines this function is the large aggregating proteoglycan of cartilage, aggrecan. Aggrecan has a relatively short half-life in cartilage...

Full description

Bibliographic Details
Main Authors: Peter M. van der Kraan, Arjan P.M. van Caam, Esmeralda N. Blaney Davidson, Martijn H.J. van den Bosch, Fons A.J. van de Loo
Format: Article
Language:English
Published: Elsevier 2024-06-01
Series:Osteoarthritis and Cartilage Open
Subjects:
Aggrecan
Cartilage
IGF
BMP
TGF-β
Online Access:http://www.sciencedirect.com/science/article/pii/S2665913124000268

Similar Items

Similar Items