Vulval squamous cell carcinoma arising from lichen sclerosus et atrophicus: A rare but not rear phenomenon

Genital ulcers may be located on the vagina, penis, anorectal or perineal areas with infectious or noninfectious etiology. Although sexually transmitted infections are a common cause of genital lesions, it is essential to consider nonvenereal disorders such as Behcet's syndrome, vesiculobullous...

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Main Authors: Vasudha A Belgaumkar, Shekhar N Pradhan, Neelamkumari Bhatt, Dhanshri D Gangode
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2023-01-01
Series:Clinical Dermatology Review
Subjects:
Online Access:http://www.cdriadvlkn.org/article.asp?issn=2542-551X;year=2023;volume=7;issue=3;spage=284;epage=287;aulast=Belgaumkar
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author Vasudha A Belgaumkar
Shekhar N Pradhan
Neelamkumari Bhatt
Dhanshri D Gangode
author_facet Vasudha A Belgaumkar
Shekhar N Pradhan
Neelamkumari Bhatt
Dhanshri D Gangode
author_sort Vasudha A Belgaumkar
collection DOAJ
description Genital ulcers may be located on the vagina, penis, anorectal or perineal areas with infectious or noninfectious etiology. Although sexually transmitted infections are a common cause of genital lesions, it is essential to consider nonvenereal disorders such as Behcet's syndrome, vesiculobullous disease, pyoderma gangrenosum, and malignant tumors in the differential diagnosis. Often, long-neglected benign and premalignant lesions which are hitherto unnoticed may undergo malignant transformation. Herein, we report a woman presenting with recurrent lower urinary tract complaints and a nonhealing ulcer over labia majora, eventually diagnosed with vulval squamous cell carcinoma arising from the underlying lesions of lichen sclerosus et atrophicus. This case emphasizes the importance of early detection and vigilant management of such disorders which may often be asymptomatic and hence remain neglected.
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spelling doaj.art-b72a599036bb42af8a360a635d2198492023-10-26T06:14:05ZengWolters Kluwer Medknow PublicationsClinical Dermatology Review2542-551X2542-55282023-01-017328428710.4103/cdr.cdr_108_21Vulval squamous cell carcinoma arising from lichen sclerosus et atrophicus: A rare but not rear phenomenonVasudha A BelgaumkarShekhar N PradhanNeelamkumari BhattDhanshri D GangodeGenital ulcers may be located on the vagina, penis, anorectal or perineal areas with infectious or noninfectious etiology. Although sexually transmitted infections are a common cause of genital lesions, it is essential to consider nonvenereal disorders such as Behcet's syndrome, vesiculobullous disease, pyoderma gangrenosum, and malignant tumors in the differential diagnosis. Often, long-neglected benign and premalignant lesions which are hitherto unnoticed may undergo malignant transformation. Herein, we report a woman presenting with recurrent lower urinary tract complaints and a nonhealing ulcer over labia majora, eventually diagnosed with vulval squamous cell carcinoma arising from the underlying lesions of lichen sclerosus et atrophicus. This case emphasizes the importance of early detection and vigilant management of such disorders which may often be asymptomatic and hence remain neglected.http://www.cdriadvlkn.org/article.asp?issn=2542-551X;year=2023;volume=7;issue=3;spage=284;epage=287;aulast=Belgaumkardysplasticlichen sclerosussquamous cell carcinoma
spellingShingle Vasudha A Belgaumkar
Shekhar N Pradhan
Neelamkumari Bhatt
Dhanshri D Gangode
Vulval squamous cell carcinoma arising from lichen sclerosus et atrophicus: A rare but not rear phenomenon
Clinical Dermatology Review
dysplastic
lichen sclerosus
squamous cell carcinoma
title Vulval squamous cell carcinoma arising from lichen sclerosus et atrophicus: A rare but not rear phenomenon
title_full Vulval squamous cell carcinoma arising from lichen sclerosus et atrophicus: A rare but not rear phenomenon
title_fullStr Vulval squamous cell carcinoma arising from lichen sclerosus et atrophicus: A rare but not rear phenomenon
title_full_unstemmed Vulval squamous cell carcinoma arising from lichen sclerosus et atrophicus: A rare but not rear phenomenon
title_short Vulval squamous cell carcinoma arising from lichen sclerosus et atrophicus: A rare but not rear phenomenon
title_sort vulval squamous cell carcinoma arising from lichen sclerosus et atrophicus a rare but not rear phenomenon
topic dysplastic
lichen sclerosus
squamous cell carcinoma
url http://www.cdriadvlkn.org/article.asp?issn=2542-551X;year=2023;volume=7;issue=3;spage=284;epage=287;aulast=Belgaumkar
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AT shekharnpradhan vulvalsquamouscellcarcinomaarisingfromlichensclerosusetatrophicusararebutnotrearphenomenon
AT neelamkumaribhatt vulvalsquamouscellcarcinomaarisingfromlichensclerosusetatrophicusararebutnotrearphenomenon
AT dhanshridgangode vulvalsquamouscellcarcinomaarisingfromlichensclerosusetatrophicusararebutnotrearphenomenon