Host Genetic Liability for Severe COVID-19 Associates with Alcohol Drinking Behavior and Diabetic Outcomes in Participants of European Descent

Host Genetic Liability for Severe COVID-19 Associates with Alcohol Drinking Behavior and Diabetic Outcomes in Participants of European Descent

Risk factors and long-term consequences of COVID-19 infection are unclear but can be investigated with large-scale genomic data. To distinguish correlation from causation, we performed in-silico analyses of three COVID-19 outcomes (N > 1,000,000). We show genetic correlation and putative caus...

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Bibliographic Details
Main Authors: Frank R Wendt, Antonella De Lillo, Gita A Pathak, Flavio De Angelis, COVID-19 Host Genetics Initiative, Renato Polimanti
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-12-01
Series:Frontiers in Genetics
Subjects:
alcohol
causal inference
COVID-19
diabetes
genetic overlap
SARS-CoV-2
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2021.765247/full

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