Copy number of 8q24.3 drives HSF1 expression and patient outcome in cancer: an individual patient data meta-analysis

Copy number of 8q24.3 drives HSF1 expression and patient outcome in cancer: an individual patient data meta-analysis

Abstract Background The heat-shock transcription factor 1 (HSF1) has been linked to cell proliferation and survival in cancer and has been proposed as a biomarker for poor prognosis. Here, we assessed the role of HSF1 expression in relation to copy number alteration (CNA) and cancer prognosis. Metho...

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Bibliographic Details
Main Authors: Nele Brusselaers, Karl Ekwall, Mickael Durand-Dubief
Format: Article
Language:English
Published: BMC 2019-11-01
Series:Human Genomics
Subjects:
Copy number alteration
8q24.3
HSF1
Individual patient data meta-analysis
Patient outcome
Online Access:http://link.springer.com/article/10.1186/s40246-019-0241-3

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