Estimation of Blood Oxygen Saturation in the Circulation Circuit for Extracorporeal Membrane Oxygenation
Extracorporeal membrane oxygenation (ECMO) is a treatment that supports heart and lung functions with a circulation circuit external to the body. In ECMO, it is important to monitor blood oxygen saturation (SO<sub>2</sub>) in the circulation tube. As a means of continuous SO<sub>2&...
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IEEE
2019-01-01
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| Series: | IEEE Access |
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| Online Access: | https://ieeexplore.ieee.org/document/8865042/ |
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| author | Kazuya Nakano Makoto Adachi Takashi Ohnishi Yutaka Furukawa Taka-Aki Nakada Shigeto Oda Hideaki Haneishi |
| author_facet | Kazuya Nakano Makoto Adachi Takashi Ohnishi Yutaka Furukawa Taka-Aki Nakada Shigeto Oda Hideaki Haneishi |
| author_sort | Kazuya Nakano |
| collection | DOAJ |
| description | Extracorporeal membrane oxygenation (ECMO) is a treatment that supports heart and lung functions with a circulation circuit external to the body. In ECMO, it is important to monitor blood oxygen saturation (SO<sub>2</sub>) in the circulation tube. As a means of continuous SO<sub>2</sub> measuring, a special connector is inserted into the circuit. However, this method is unsuitable for emergency treatment. Therefore, it is necessary to measure blood SO<sub>2</sub> in the tube without the connector. However, this creates problems for SO<sub>2</sub> estimation, due to varying blood concentration and flow velocity, hemolysis, and wall thickness of the tube. Therefore, we developed a SO<sub>2</sub> estimation method that can calibrate the variation in blood concentration. The method is based on a conversion model between absorbance and SO<sub>2</sub> (CAS), which varies depending on the concentration. In this method, the CAS for the SO<sub>2</sub> estimation is estimated by CAS corresponding to two blood samples prepared in advance with different concentrations. The experiment for SO<sub>2</sub> estimation was conducted with a spectroscope, a halogen light source, and a cut tube. We confirmed that the average error of estimated SO<sub>2</sub> against the SO<sub>2</sub> values measured by a gas analysis was 3.8% within a blood volume concentration range from 50 to 90%. In future work, to improve the estimation accuracy, we will improve our method by investigating other factors that may affect the accuracy. |
| first_indexed | 2024-12-14T14:54:24Z |
| format | Article |
| id | doaj.art-b736b05404e04b2ab1334762ff00fdd4 |
| institution | Directory Open Access Journal |
| issn | 2169-3536 |
| language | English |
| last_indexed | 2024-12-14T14:54:24Z |
| publishDate | 2019-01-01 |
| publisher | IEEE |
| record_format | Article |
| series | IEEE Access |
| spelling | doaj.art-b736b05404e04b2ab1334762ff00fdd42022-12-21T22:57:02ZengIEEEIEEE Access2169-35362019-01-01715505715506310.1109/ACCESS.2019.29469058865042Estimation of Blood Oxygen Saturation in the Circulation Circuit for Extracorporeal Membrane OxygenationKazuya Nakano0https://orcid.org/0000-0002-7639-1920Makoto Adachi1Takashi Ohnishi2Yutaka Furukawa3Taka-Aki Nakada4Shigeto Oda5Hideaki Haneishi6Center for Frontier Medical Engineering, Chiba University, Chiba, JapanGraduate School of Science and Engineering, Chiba University, Chiba, JapanCenter for Frontier Medical Engineering, Chiba University, Chiba, JapanChiba University Hospital, Chiba, JapanGraduate School of Medicine, Emergency and Critical Care Medicine, Chiba University, Chiba, JapanGraduate School of Medicine, Emergency and Critical Care Medicine, Chiba University, Chiba, JapanCenter for Frontier Medical Engineering, Chiba University, Chiba, JapanExtracorporeal membrane oxygenation (ECMO) is a treatment that supports heart and lung functions with a circulation circuit external to the body. In ECMO, it is important to monitor blood oxygen saturation (SO<sub>2</sub>) in the circulation tube. As a means of continuous SO<sub>2</sub> measuring, a special connector is inserted into the circuit. However, this method is unsuitable for emergency treatment. Therefore, it is necessary to measure blood SO<sub>2</sub> in the tube without the connector. However, this creates problems for SO<sub>2</sub> estimation, due to varying blood concentration and flow velocity, hemolysis, and wall thickness of the tube. Therefore, we developed a SO<sub>2</sub> estimation method that can calibrate the variation in blood concentration. The method is based on a conversion model between absorbance and SO<sub>2</sub> (CAS), which varies depending on the concentration. In this method, the CAS for the SO<sub>2</sub> estimation is estimated by CAS corresponding to two blood samples prepared in advance with different concentrations. The experiment for SO<sub>2</sub> estimation was conducted with a spectroscope, a halogen light source, and a cut tube. We confirmed that the average error of estimated SO<sub>2</sub> against the SO<sub>2</sub> values measured by a gas analysis was 3.8% within a blood volume concentration range from 50 to 90%. In future work, to improve the estimation accuracy, we will improve our method by investigating other factors that may affect the accuracy.https://ieeexplore.ieee.org/document/8865042/Biomedical monitoringspectroscopycirculators |
| spellingShingle | Kazuya Nakano Makoto Adachi Takashi Ohnishi Yutaka Furukawa Taka-Aki Nakada Shigeto Oda Hideaki Haneishi Estimation of Blood Oxygen Saturation in the Circulation Circuit for Extracorporeal Membrane Oxygenation IEEE Access Biomedical monitoring spectroscopy circulators |
| title | Estimation of Blood Oxygen Saturation in the Circulation Circuit for Extracorporeal Membrane Oxygenation |
| title_full | Estimation of Blood Oxygen Saturation in the Circulation Circuit for Extracorporeal Membrane Oxygenation |
| title_fullStr | Estimation of Blood Oxygen Saturation in the Circulation Circuit for Extracorporeal Membrane Oxygenation |
| title_full_unstemmed | Estimation of Blood Oxygen Saturation in the Circulation Circuit for Extracorporeal Membrane Oxygenation |
| title_short | Estimation of Blood Oxygen Saturation in the Circulation Circuit for Extracorporeal Membrane Oxygenation |
| title_sort | estimation of blood oxygen saturation in the circulation circuit for extracorporeal membrane oxygenation |
| topic | Biomedical monitoring spectroscopy circulators |
| url | https://ieeexplore.ieee.org/document/8865042/ |
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