Removal of false positives in metagenomics-based taxonomy profiling via targeting Type IIB restriction sites
Abstract Accurate species identification and abundance estimation are critical for the interpretation of whole metagenome sequencing (WMS) data. Yet, existing metagenomic profilers suffer from false-positive identifications, which can account for more than 90% of total identified species. Here, by l...
Main Authors: | Zheng Sun, Jiang Liu, Meng Zhang, Tong Wang, Shi Huang, Scott T. Weiss, Yang-Yu Liu |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-09-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-023-41099-8 |
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