Upconversion nanoparticle as a theranostic agent for tumor imaging and therapy

Upconversion nanoparticles (UCNPs) as a promising material are widely studied due to their unique optical properties. The material can be excited by long wavelength light and emit visible wavelength light through multiphoton absorption. This property makes the particles highly attractive candidates...

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Bibliographic Details
Main Authors: Wenkai Fang, Yanchun Wei
Format: Article
Language:English
Published: World Scientific Publishing 2016-07-01
Series:Journal of Innovative Optical Health Sciences
Subjects:
Online Access:http://www.worldscientific.com/doi/pdf/10.1142/S1793545816300068
Description
Summary:Upconversion nanoparticles (UCNPs) as a promising material are widely studied due to their unique optical properties. The material can be excited by long wavelength light and emit visible wavelength light through multiphoton absorption. This property makes the particles highly attractive candidates for bioimaging and therapy application. This review aims at summarizing the synthesis and modification of UCNPs, especially the applications of UCNPs as a theranostic agent for tumor imaging and therapy. The biocompatibility and toxicity of UCNPs are also further discussed. Finally, we discuss the challenges and opportunities in the development of UCNP-based nanoplatforms for tumor imaging and therapy.
ISSN:1793-5458
1793-7205