Upconversion nanoparticle as a theranostic agent for tumor imaging and therapy
Upconversion nanoparticles (UCNPs) as a promising material are widely studied due to their unique optical properties. The material can be excited by long wavelength light and emit visible wavelength light through multiphoton absorption. This property makes the particles highly attractive candidates...
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Format: | Article |
Language: | English |
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World Scientific Publishing
2016-07-01
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Series: | Journal of Innovative Optical Health Sciences |
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Online Access: | http://www.worldscientific.com/doi/pdf/10.1142/S1793545816300068 |
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author | Wenkai Fang Yanchun Wei |
author_facet | Wenkai Fang Yanchun Wei |
author_sort | Wenkai Fang |
collection | DOAJ |
description | Upconversion nanoparticles (UCNPs) as a promising material are widely studied due to their unique optical properties. The material can be excited by long wavelength light and emit visible wavelength light through multiphoton absorption. This property makes the particles highly attractive candidates for bioimaging and therapy application. This review aims at summarizing the synthesis and modification of UCNPs, especially the applications of UCNPs as a theranostic agent for tumor imaging and therapy. The biocompatibility and toxicity of UCNPs are also further discussed. Finally, we discuss the challenges and opportunities in the development of UCNP-based nanoplatforms for tumor imaging and therapy. |
first_indexed | 2024-12-12T01:43:49Z |
format | Article |
id | doaj.art-b737d1ac85ad4c6cb35e4229f09cbe5f |
institution | Directory Open Access Journal |
issn | 1793-5458 1793-7205 |
language | English |
last_indexed | 2024-12-12T01:43:49Z |
publishDate | 2016-07-01 |
publisher | World Scientific Publishing |
record_format | Article |
series | Journal of Innovative Optical Health Sciences |
spelling | doaj.art-b737d1ac85ad4c6cb35e4229f09cbe5f2022-12-22T00:42:38ZengWorld Scientific PublishingJournal of Innovative Optical Health Sciences1793-54581793-72052016-07-01941630006-11630006-2010.1142/S179354581630006810.1142/S1793545816300068Upconversion nanoparticle as a theranostic agent for tumor imaging and therapyWenkai Fang0Yanchun Wei1Ministry of Education Key Laboratory of Laser, Life Science & Institute of Laser Life Science, College of Biophotonics South China Normal University, Guangzhou 510631, P. R. ChinaMinistry of Education Key Laboratory of Laser, Life Science & Institute of Laser Life Science, College of Biophotonics South China Normal University, Guangzhou 510631, P. R. ChinaUpconversion nanoparticles (UCNPs) as a promising material are widely studied due to their unique optical properties. The material can be excited by long wavelength light and emit visible wavelength light through multiphoton absorption. This property makes the particles highly attractive candidates for bioimaging and therapy application. This review aims at summarizing the synthesis and modification of UCNPs, especially the applications of UCNPs as a theranostic agent for tumor imaging and therapy. The biocompatibility and toxicity of UCNPs are also further discussed. Finally, we discuss the challenges and opportunities in the development of UCNP-based nanoplatforms for tumor imaging and therapy.http://www.worldscientific.com/doi/pdf/10.1142/S1793545816300068Laserupconversion materialbioimagingtoxicity |
spellingShingle | Wenkai Fang Yanchun Wei Upconversion nanoparticle as a theranostic agent for tumor imaging and therapy Journal of Innovative Optical Health Sciences Laser upconversion material bioimaging toxicity |
title | Upconversion nanoparticle as a theranostic agent for tumor imaging and therapy |
title_full | Upconversion nanoparticle as a theranostic agent for tumor imaging and therapy |
title_fullStr | Upconversion nanoparticle as a theranostic agent for tumor imaging and therapy |
title_full_unstemmed | Upconversion nanoparticle as a theranostic agent for tumor imaging and therapy |
title_short | Upconversion nanoparticle as a theranostic agent for tumor imaging and therapy |
title_sort | upconversion nanoparticle as a theranostic agent for tumor imaging and therapy |
topic | Laser upconversion material bioimaging toxicity |
url | http://www.worldscientific.com/doi/pdf/10.1142/S1793545816300068 |
work_keys_str_mv | AT wenkaifang upconversionnanoparticleasatheranosticagentfortumorimagingandtherapy AT yanchunwei upconversionnanoparticleasatheranosticagentfortumorimagingandtherapy |