Upconversion nanoparticle as a theranostic agent for tumor imaging and therapy

Upconversion nanoparticles (UCNPs) as a promising material are widely studied due to their unique optical properties. The material can be excited by long wavelength light and emit visible wavelength light through multiphoton absorption. This property makes the particles highly attractive candidates...

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Main Authors: Wenkai Fang, Yanchun Wei
Format: Article
Language:English
Published: World Scientific Publishing 2016-07-01
Series:Journal of Innovative Optical Health Sciences
Subjects:
Online Access:http://www.worldscientific.com/doi/pdf/10.1142/S1793545816300068
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author Wenkai Fang
Yanchun Wei
author_facet Wenkai Fang
Yanchun Wei
author_sort Wenkai Fang
collection DOAJ
description Upconversion nanoparticles (UCNPs) as a promising material are widely studied due to their unique optical properties. The material can be excited by long wavelength light and emit visible wavelength light through multiphoton absorption. This property makes the particles highly attractive candidates for bioimaging and therapy application. This review aims at summarizing the synthesis and modification of UCNPs, especially the applications of UCNPs as a theranostic agent for tumor imaging and therapy. The biocompatibility and toxicity of UCNPs are also further discussed. Finally, we discuss the challenges and opportunities in the development of UCNP-based nanoplatforms for tumor imaging and therapy.
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spelling doaj.art-b737d1ac85ad4c6cb35e4229f09cbe5f2022-12-22T00:42:38ZengWorld Scientific PublishingJournal of Innovative Optical Health Sciences1793-54581793-72052016-07-01941630006-11630006-2010.1142/S179354581630006810.1142/S1793545816300068Upconversion nanoparticle as a theranostic agent for tumor imaging and therapyWenkai Fang0Yanchun Wei1Ministry of Education Key Laboratory of Laser, Life Science & Institute of Laser Life Science, College of Biophotonics South China Normal University, Guangzhou 510631, P. R. ChinaMinistry of Education Key Laboratory of Laser, Life Science & Institute of Laser Life Science, College of Biophotonics South China Normal University, Guangzhou 510631, P. R. ChinaUpconversion nanoparticles (UCNPs) as a promising material are widely studied due to their unique optical properties. The material can be excited by long wavelength light and emit visible wavelength light through multiphoton absorption. This property makes the particles highly attractive candidates for bioimaging and therapy application. This review aims at summarizing the synthesis and modification of UCNPs, especially the applications of UCNPs as a theranostic agent for tumor imaging and therapy. The biocompatibility and toxicity of UCNPs are also further discussed. Finally, we discuss the challenges and opportunities in the development of UCNP-based nanoplatforms for tumor imaging and therapy.http://www.worldscientific.com/doi/pdf/10.1142/S1793545816300068Laserupconversion materialbioimagingtoxicity
spellingShingle Wenkai Fang
Yanchun Wei
Upconversion nanoparticle as a theranostic agent for tumor imaging and therapy
Journal of Innovative Optical Health Sciences
Laser
upconversion material
bioimaging
toxicity
title Upconversion nanoparticle as a theranostic agent for tumor imaging and therapy
title_full Upconversion nanoparticle as a theranostic agent for tumor imaging and therapy
title_fullStr Upconversion nanoparticle as a theranostic agent for tumor imaging and therapy
title_full_unstemmed Upconversion nanoparticle as a theranostic agent for tumor imaging and therapy
title_short Upconversion nanoparticle as a theranostic agent for tumor imaging and therapy
title_sort upconversion nanoparticle as a theranostic agent for tumor imaging and therapy
topic Laser
upconversion material
bioimaging
toxicity
url http://www.worldscientific.com/doi/pdf/10.1142/S1793545816300068
work_keys_str_mv AT wenkaifang upconversionnanoparticleasatheranosticagentfortumorimagingandtherapy
AT yanchunwei upconversionnanoparticleasatheranosticagentfortumorimagingandtherapy