Knockdown of SEMA7A alleviates MPP+‐induced apoptosis and inflammation in BV2 microglia via PPAR‐γ activation and MAPK inactivation

Knockdown of SEMA7A alleviates MPP+‐induced apoptosis and inflammation in BV2 microglia via PPAR‐γ activation and MAPK inactivation

Abstract Introduction The inflammation mediated by microglial cells plays an important role in the process of neurodegenerative diseases. Recent evidence indicates that semaphorin 7A (SEMA7A) is implicated in various neurodegenerative diseases, but whether it plays a role in Parkinson's disease...

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Bibliographic Details
Main Authors: Weinan Qi, Dan Zeng, Xiaoshuan Xiong, Qun Hu
Format: Article
Language:English
Published: Wiley 2023-01-01
Series:Immunity, Inflammation and Disease
Subjects:
apoptosis
inflammation
MAPK
microglia
PPAR‐γ
SEMA7A
Online Access:https://doi.org/10.1002/iid3.756

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