REM Sleep and Endothermy: Potential Sites and Mechanism of a Reciprocal Interference
Numerous data show a reciprocal interaction between REM sleep and thermoregulation. During REM sleep, the function of thermoregulation appears to be impaired; from the other hand, the tonic activation of thermogenesis, such as during cold exposure, suppresses REM sleep occurrence. Recently, both the...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2017-08-01
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| Series: | Frontiers in Physiology |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/article/10.3389/fphys.2017.00624/full |
| _version_ | 1818845730860695552 |
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| author | Matteo Cerri Marco Luppi Domenico Tupone Giovanni Zamboni Roberto Amici |
| author_facet | Matteo Cerri Marco Luppi Domenico Tupone Giovanni Zamboni Roberto Amici |
| author_sort | Matteo Cerri |
| collection | DOAJ |
| description | Numerous data show a reciprocal interaction between REM sleep and thermoregulation. During REM sleep, the function of thermoregulation appears to be impaired; from the other hand, the tonic activation of thermogenesis, such as during cold exposure, suppresses REM sleep occurrence. Recently, both the central neural network controlling REM sleep and the central neural network controlling thermoregulation have been progressively unraveled. Thermoregulation was shown to be controlled by a central “core” circuit, responsible for the maintenance of body temperature, modulated by a set of accessory areas. REM sleep was suggested to be controlled by a group of hypothalamic neurons overlooking at the REM sleep generating circuits within the brainstem. The two networks overlap in a few areas, and in this review, we will suggest that in such overlap may reside the explanation of the reciprocal interaction between REM sleep and thermoregulation. Considering the peculiar modulation of thermoregulation by REM sleep the result of their coincidental evolution, REM sleep may therefore be seen as a period of transient heterothermy. |
| first_indexed | 2024-12-19T05:34:19Z |
| format | Article |
| id | doaj.art-b741c97ef1894d18b8eb15eb4b301da9 |
| institution | Directory Open Access Journal |
| issn | 1664-042X |
| language | English |
| last_indexed | 2024-12-19T05:34:19Z |
| publishDate | 2017-08-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Physiology |
| spelling | doaj.art-b741c97ef1894d18b8eb15eb4b301da92022-12-21T20:34:10ZengFrontiers Media S.A.Frontiers in Physiology1664-042X2017-08-01810.3389/fphys.2017.00624276990REM Sleep and Endothermy: Potential Sites and Mechanism of a Reciprocal InterferenceMatteo CerriMarco LuppiDomenico TuponeGiovanni ZamboniRoberto AmiciNumerous data show a reciprocal interaction between REM sleep and thermoregulation. During REM sleep, the function of thermoregulation appears to be impaired; from the other hand, the tonic activation of thermogenesis, such as during cold exposure, suppresses REM sleep occurrence. Recently, both the central neural network controlling REM sleep and the central neural network controlling thermoregulation have been progressively unraveled. Thermoregulation was shown to be controlled by a central “core” circuit, responsible for the maintenance of body temperature, modulated by a set of accessory areas. REM sleep was suggested to be controlled by a group of hypothalamic neurons overlooking at the REM sleep generating circuits within the brainstem. The two networks overlap in a few areas, and in this review, we will suggest that in such overlap may reside the explanation of the reciprocal interaction between REM sleep and thermoregulation. Considering the peculiar modulation of thermoregulation by REM sleep the result of their coincidental evolution, REM sleep may therefore be seen as a period of transient heterothermy.http://journal.frontiersin.org/article/10.3389/fphys.2017.00624/fullREM sleepthermoregulationheterothermymedian preoptic nucleusperiaqueductal graylateral parabrachial nucleus |
| spellingShingle | Matteo Cerri Marco Luppi Domenico Tupone Giovanni Zamboni Roberto Amici REM Sleep and Endothermy: Potential Sites and Mechanism of a Reciprocal Interference Frontiers in Physiology REM sleep thermoregulation heterothermy median preoptic nucleus periaqueductal gray lateral parabrachial nucleus |
| title | REM Sleep and Endothermy: Potential Sites and Mechanism of a Reciprocal Interference |
| title_full | REM Sleep and Endothermy: Potential Sites and Mechanism of a Reciprocal Interference |
| title_fullStr | REM Sleep and Endothermy: Potential Sites and Mechanism of a Reciprocal Interference |
| title_full_unstemmed | REM Sleep and Endothermy: Potential Sites and Mechanism of a Reciprocal Interference |
| title_short | REM Sleep and Endothermy: Potential Sites and Mechanism of a Reciprocal Interference |
| title_sort | rem sleep and endothermy potential sites and mechanism of a reciprocal interference |
| topic | REM sleep thermoregulation heterothermy median preoptic nucleus periaqueductal gray lateral parabrachial nucleus |
| url | http://journal.frontiersin.org/article/10.3389/fphys.2017.00624/full |
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