Radiotherapy‐Induced Astrocyte Senescence Promotes an Immunosuppressive Microenvironment in Glioblastoma to Facilitate Tumor Regrowth

Radiotherapy‐Induced Astrocyte Senescence Promotes an Immunosuppressive Microenvironment in Glioblastoma to Facilitate Tumor Regrowth

Abstract Accumulating evidence suggests that changes in the tumor microenvironment caused by radiotherapy are closely related to the recurrence of glioma. However, the mechanisms by which such radiation‐induced changes are involved in tumor regrowth have not yet been fully investigated. In the prese...

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Bibliographic Details
Main Authors: Jianxiong Ji, Kaikai Ding, Bo Cheng, Xin Zhang, Tao Luo, Bin Huang, Hao Yu, Yike Chen, Xiaohui Xu, Haopu Lin, Jiayin Zhou, Tingtin Wang, Mengmeng Jin, Aixia Liu, Danfang Yan, Fuyi Liu, Chun Wang, Jingsen Chen, Feng Yan, Lin Wang, Jianmin Zhang, Senxiang Yan, Jian Wang, Xingang Li, Gao Chen
Format: Article
Language:English
Published: Wiley 2024-04-01
Series:Advanced Science
Subjects:
astrocytes
Glioma
myeloid inflammatory cells
radiation‐induced senescence
senolytic agents
Online Access:https://doi.org/10.1002/advs.202304609

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