Integrative Analysis of 5-Hydroxymethylcytosine and Transcriptional Profiling Identified 5hmC-Modified lncRNA Panel as Non-Invasive Biomarkers for Diagnosis and Prognosis of Pancreatic Cancer

Integrative Analysis of 5-Hydroxymethylcytosine and Transcriptional Profiling Identified 5hmC-Modified lncRNA Panel as Non-Invasive Biomarkers for Diagnosis and Prognosis of Pancreatic Cancer

Pancreatic adenocarcinoma (PAAD) is the fourth leading cause of cancer-related deaths worldwide. 5-Hydroxymethylcytosine (5hmC)-mediated epigenetic regulation has been reported to be involved in cancer pathobiology and has emerged to be promising biomarkers for cancer diagnosis and prognosis. Howeve...

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Bibliographic Details
Main Authors:	Shuangquan Li, Yiran Wang, Caiyun Wen, Mingxi Zhu, Meihao Wang, Guoquan Cao
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-03-01
Series:	Frontiers in Cell and Developmental Biology
Subjects:	5-hydroxymethylcytosine pancreatic cancer machining learning long non-coding RNA non-invasive biomarker
Online Access:	https://www.frontiersin.org/articles/10.3389/fcell.2022.845641/full

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