ASSESMENT OF IL–12 ACTIVITY IN PATIENTS WITH HEMORRHAGIC FEVER WITH RENAL SYNDROME ASSOCIATED WITH SEOUL SEROTYPE
Abstract. Immunopathological mechanisms of hemorrhagic fever with renal syndrome (HFRS) are very complex and are recognized as the cause of the basic pathophysiological abnormalities in this infection. In this report the results of investigation of IL12р70 and IL12р40 levels in serum of 22 patients...
| Main Authors: | , |
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| Format: | Article |
| Language: | Russian |
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St. Petersburg branch of the Russian Association of Allergologists and Clinical Immunologists
2014-07-01
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| Series: | Медицинская иммунология |
| Subjects: | |
| Online Access: | https://www.mimmun.ru/mimmun/article/view/442 |
| _version_ | 1797198112369934336 |
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| author | L. Yu. Pereverten E. V. Markelova |
| author_facet | L. Yu. Pereverten E. V. Markelova |
| author_sort | L. Yu. Pereverten |
| collection | DOAJ |
| description | Abstract. Immunopathological mechanisms of hemorrhagic fever with renal syndrome (HFRS) are very complex and are recognized as the cause of the basic pathophysiological abnormalities in this infection. In this report the results of investigation of IL12р70 and IL12р40 levels in serum of 22 patients with HFRS of different severity in dynamics of illness have been stated. High activity of IL12р70 in the acute phase of HFRS, associated with serotype Seoul virus has been determined. Probably, the influence of the other factors of immune system along with IL12р40 promoted the development of relative failure of cellular immunity in HFRS. (Med. Immunol., 2005, vol.7, № 1, pp 89592) |
| first_indexed | 2024-03-08T05:50:58Z |
| format | Article |
| id | doaj.art-b74bce08777f4109bba8d4eea489b2d8 |
| institution | Directory Open Access Journal |
| issn | 1563-0625 2313-741X |
| language | Russian |
| last_indexed | 2024-04-24T06:54:41Z |
| publishDate | 2014-07-01 |
| publisher | St. Petersburg branch of the Russian Association of Allergologists and Clinical Immunologists |
| record_format | Article |
| series | Медицинская иммунология |
| spelling | doaj.art-b74bce08777f4109bba8d4eea489b2d82024-04-22T13:07:36ZrusSt. Petersburg branch of the Russian Association of Allergologists and Clinical ImmunologistsМедицинская иммунология1563-06252313-741X2014-07-0171899210.15789/1563-0625-2005-1-89-92439ASSESMENT OF IL–12 ACTIVITY IN PATIENTS WITH HEMORRHAGIC FEVER WITH RENAL SYNDROME ASSOCIATED WITH SEOUL SEROTYPEL. Yu. Pereverten0E. V. Markelova1Владивостокский государственный медицинский университетВладивостокский государственный медицинский университетAbstract. Immunopathological mechanisms of hemorrhagic fever with renal syndrome (HFRS) are very complex and are recognized as the cause of the basic pathophysiological abnormalities in this infection. In this report the results of investigation of IL12р70 and IL12р40 levels in serum of 22 patients with HFRS of different severity in dynamics of illness have been stated. High activity of IL12р70 in the acute phase of HFRS, associated with serotype Seoul virus has been determined. Probably, the influence of the other factors of immune system along with IL12р40 promoted the development of relative failure of cellular immunity in HFRS. (Med. Immunol., 2005, vol.7, № 1, pp 89592)https://www.mimmun.ru/mimmun/article/view/442immunopathegenesiscellular immunityhemorrhagic fever with renal syndrome |
| spellingShingle | L. Yu. Pereverten E. V. Markelova ASSESMENT OF IL–12 ACTIVITY IN PATIENTS WITH HEMORRHAGIC FEVER WITH RENAL SYNDROME ASSOCIATED WITH SEOUL SEROTYPE Медицинская иммунология immunopathegenesis cellular immunity hemorrhagic fever with renal syndrome |
| title | ASSESMENT OF IL–12 ACTIVITY IN PATIENTS WITH HEMORRHAGIC FEVER WITH RENAL SYNDROME ASSOCIATED WITH SEOUL SEROTYPE |
| title_full | ASSESMENT OF IL–12 ACTIVITY IN PATIENTS WITH HEMORRHAGIC FEVER WITH RENAL SYNDROME ASSOCIATED WITH SEOUL SEROTYPE |
| title_fullStr | ASSESMENT OF IL–12 ACTIVITY IN PATIENTS WITH HEMORRHAGIC FEVER WITH RENAL SYNDROME ASSOCIATED WITH SEOUL SEROTYPE |
| title_full_unstemmed | ASSESMENT OF IL–12 ACTIVITY IN PATIENTS WITH HEMORRHAGIC FEVER WITH RENAL SYNDROME ASSOCIATED WITH SEOUL SEROTYPE |
| title_short | ASSESMENT OF IL–12 ACTIVITY IN PATIENTS WITH HEMORRHAGIC FEVER WITH RENAL SYNDROME ASSOCIATED WITH SEOUL SEROTYPE |
| title_sort | assesment of il 12 activity in patients with hemorrhagic fever with renal syndrome associated with seoul serotype |
| topic | immunopathegenesis cellular immunity hemorrhagic fever with renal syndrome |
| url | https://www.mimmun.ru/mimmun/article/view/442 |
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