Binomial-discrete Erlang-truncated exponential mixture and its application in cancer disease

Abstract Among diseases, cancer exhibits the fastest global spread, presenting a substantial challenge for patients, their families, and the communities they belong to. This paper is devoted to modeling such a disease as a special case. A newly proposed distribution called the binomial-discrete Erla...

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Bibliographic Details
Main Authors: Alaa R. El-Alosey, Hussein Eledum
Format: Article
Language:English
Published: Nature Portfolio 2023-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-38709-2
Description
Summary:Abstract Among diseases, cancer exhibits the fastest global spread, presenting a substantial challenge for patients, their families, and the communities they belong to. This paper is devoted to modeling such a disease as a special case. A newly proposed distribution called the binomial-discrete Erlang-truncated exponential (BDETE) is introduced. The BDETE is a mixture of binomial distribution with the number of trials (parameter $$n$$ n ) taken after a discrete Erlang-truncated exponential distribution. A comprehensive mathematical treatment of the proposed distribution and expressions of its density, cumulative distribution function, survival function, failure rate function, Quantile function, moment generating function, Shannon entropy, order statistics, and stress-strength reliability, are provided. The distribution's parameters are estimated using the maximum likelihood method. Two real-world lifetime count data sets from the cancer disease, both of which are right-skewed and over-dispersed, are fitted using the proposed BDETE distribution to evaluate its efficacy and viability. We expect the findings to become standard works in probability theory and its related fields.
ISSN:2045-2322