Drosophila E-cadherin functions in hematopoietic progenitors to maintain multipotency and block differentiation.

Drosophila E-cadherin functions in hematopoietic progenitors to maintain multipotency and block differentiation.

A fundamental question in stem cell biology concerns the regulatory strategies that control the choice between multipotency and differentiation. Drosophila blood progenitors or prohemocytes exhibit key stem cell characteristics, including multipotency, quiescence, and niche dependence. As a result,...

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Bibliographic Details
Main Authors: Hongjuan Gao, Xiaorong Wu, Nancy Fossett
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3764055?pdf=render

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