Tumor-Derived Membrane Vesicles: A Promising Tool for Personalized Immunotherapy
Tumor-derived membrane vesicles (TDMVs) are non-invasive, chemotactic, easily obtained characteristics and contain various tumor-borne substances, such as nucleic acid and proteins. The unique properties of tumor cells and membranes make them widely used in drug loading, membrane fusion and vaccines...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2022-07-01
|
| Series: | Pharmaceuticals |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1424-8247/15/7/876 |
| _version_ | 1797433207189143552 |
|---|---|
| author | Jiabin Xu Wenqiang Cao Penglai Wang Hong Liu |
| author_facet | Jiabin Xu Wenqiang Cao Penglai Wang Hong Liu |
| author_sort | Jiabin Xu |
| collection | DOAJ |
| description | Tumor-derived membrane vesicles (TDMVs) are non-invasive, chemotactic, easily obtained characteristics and contain various tumor-borne substances, such as nucleic acid and proteins. The unique properties of tumor cells and membranes make them widely used in drug loading, membrane fusion and vaccines. In particular, personalized vectors prepared using the editable properties of cells can help in the design of personalized vaccines. This review focuses on recent research on TDMV technology and its application in personalized immunotherapy. We elucidate the strengths and challenges of TDMVs to promote their application from theory to clinical practice. |
| first_indexed | 2024-03-09T10:13:44Z |
| format | Article |
| id | doaj.art-b7556e59ccc14291ab2c833a55837aaa |
| institution | Directory Open Access Journal |
| issn | 1424-8247 |
| language | English |
| last_indexed | 2024-03-09T10:13:44Z |
| publishDate | 2022-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Pharmaceuticals |
| spelling | doaj.art-b7556e59ccc14291ab2c833a55837aaa2023-12-01T22:33:42ZengMDPI AGPharmaceuticals1424-82472022-07-0115787610.3390/ph15070876Tumor-Derived Membrane Vesicles: A Promising Tool for Personalized ImmunotherapyJiabin Xu0Wenqiang Cao1Penglai Wang2Hong Liu3School of Stomatology, Xuzhou Medical University, Xuzhou 221004, ChinaZhuhai Jinan Selenium Source Nanotechnology Co., Ltd., Jinan University, Zhuhai 519000, ChinaSchool of Stomatology, Xuzhou Medical University, Xuzhou 221004, ChinaZhuhai Jinan Selenium Source Nanotechnology Co., Ltd., Jinan University, Zhuhai 519000, ChinaTumor-derived membrane vesicles (TDMVs) are non-invasive, chemotactic, easily obtained characteristics and contain various tumor-borne substances, such as nucleic acid and proteins. The unique properties of tumor cells and membranes make them widely used in drug loading, membrane fusion and vaccines. In particular, personalized vectors prepared using the editable properties of cells can help in the design of personalized vaccines. This review focuses on recent research on TDMV technology and its application in personalized immunotherapy. We elucidate the strengths and challenges of TDMVs to promote their application from theory to clinical practice.https://www.mdpi.com/1424-8247/15/7/876tumor-derived membrane vesiclescancer therapytumor vaccinepersonalized immunotherapy |
| spellingShingle | Jiabin Xu Wenqiang Cao Penglai Wang Hong Liu Tumor-Derived Membrane Vesicles: A Promising Tool for Personalized Immunotherapy Pharmaceuticals tumor-derived membrane vesicles cancer therapy tumor vaccine personalized immunotherapy |
| title | Tumor-Derived Membrane Vesicles: A Promising Tool for Personalized Immunotherapy |
| title_full | Tumor-Derived Membrane Vesicles: A Promising Tool for Personalized Immunotherapy |
| title_fullStr | Tumor-Derived Membrane Vesicles: A Promising Tool for Personalized Immunotherapy |
| title_full_unstemmed | Tumor-Derived Membrane Vesicles: A Promising Tool for Personalized Immunotherapy |
| title_short | Tumor-Derived Membrane Vesicles: A Promising Tool for Personalized Immunotherapy |
| title_sort | tumor derived membrane vesicles a promising tool for personalized immunotherapy |
| topic | tumor-derived membrane vesicles cancer therapy tumor vaccine personalized immunotherapy |
| url | https://www.mdpi.com/1424-8247/15/7/876 |
| work_keys_str_mv | AT jiabinxu tumorderivedmembranevesiclesapromisingtoolforpersonalizedimmunotherapy AT wenqiangcao tumorderivedmembranevesiclesapromisingtoolforpersonalizedimmunotherapy AT penglaiwang tumorderivedmembranevesiclesapromisingtoolforpersonalizedimmunotherapy AT hongliu tumorderivedmembranevesiclesapromisingtoolforpersonalizedimmunotherapy |