The Cytolethal Distending Toxin Effects on Mammalian Cells: A DNA Damage Perspective
The cytolethal distending toxin (CDT) is produced by many pathogenic Gram-negative bacteria and is considered as a virulence factor. In human cells, CDT exposure leads to a unique cytotoxicity associated with a characteristic cell distension and induces a cell cycle arrest dependent on the DNA dama...
Main Authors: | Elisabeth Bezine, Julien Vignard, Gladys Mirey |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2014-06-01
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Series: | Cells |
Subjects: | |
Online Access: | http://www.mdpi.com/2073-4409/3/2/592 |
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