Health economic analysis of the integrated cognitive assessment tool to aid dementia diagnosis in the United Kingdom

ObjectivesThe aim of this study was to develop a comprehensive economic evaluation of the integrated cognitive assessment (ICA) tool compared with standard cognitive tests when used for dementia screening in primary care and for initial patient triage in memory clinics.MethodsICA was compared with s...

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Main Authors: Judith Shore, Chris Kalafatis, Angela Stainthorpe, Mohammad Hadi Modarres, Seyed-Mahdi Khaligh-Razavi
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-09-01
Series:Frontiers in Public Health
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fpubh.2023.1240901/full
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author Judith Shore
Chris Kalafatis
Chris Kalafatis
Angela Stainthorpe
Mohammad Hadi Modarres
Seyed-Mahdi Khaligh-Razavi
Seyed-Mahdi Khaligh-Razavi
author_facet Judith Shore
Chris Kalafatis
Chris Kalafatis
Angela Stainthorpe
Mohammad Hadi Modarres
Seyed-Mahdi Khaligh-Razavi
Seyed-Mahdi Khaligh-Razavi
author_sort Judith Shore
collection DOAJ
description ObjectivesThe aim of this study was to develop a comprehensive economic evaluation of the integrated cognitive assessment (ICA) tool compared with standard cognitive tests when used for dementia screening in primary care and for initial patient triage in memory clinics.MethodsICA was compared with standard of care comprising a mixture of cognitive assessment tools over a lifetime horizon and employing the UK health and social care perspective. The model combined a decision tree to capture the initial outcomes of the cognitive testing with a Markov structure that estimated long-term outcomes of people with dementia. Quality of life outcomes were quantified using quality-adjusted life years (QALYs), and the economic benefits were assessed using net monetary benefit (NMB). Both costs and QALYs were discounted at 3.5% per annum and cost-effectiveness was assessed using a threshold of £20,000 per QALY gained.ResultsICA dominated standard cognitive assessment tools in both the primary care and memory clinic settings. Introduction of the ICA tool was estimated to result in a lifetime cost saving of approximately £123 and £226 per person in primary care and memory clinics, respectively. QALY gains associated with early diagnosis were modest (0.0016 in primary care and 0.0027 in memory clinic). The net monetary benefit (NMB) of ICA introduction was estimated at £154 in primary care and £281 in the memory clinic settings.ConclusionIntroduction of ICA as a tool to screen primary care patients for dementia and perform initial triage in memory clinics could be cost saving to the UK public health and social care payer.
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spelling doaj.art-b76881e98300418490ffa5ffb6cd6dc32023-09-29T12:07:34ZengFrontiers Media S.A.Frontiers in Public Health2296-25652023-09-011110.3389/fpubh.2023.12409011240901Health economic analysis of the integrated cognitive assessment tool to aid dementia diagnosis in the United KingdomJudith Shore0Chris Kalafatis1Chris Kalafatis2Angela Stainthorpe3Mohammad Hadi Modarres4Seyed-Mahdi Khaligh-Razavi5Seyed-Mahdi Khaligh-Razavi6York Health Economics Consortium, University of York, York, United KingdomCognetivity Ltd., London, United KingdomDepartment of Old Age Psychiatry, South London and Maudsley NHS Foundation Trust, King’s College London, London, United KingdomYork Health Economics Consortium, University of York, York, United KingdomCognetivity Ltd., London, United KingdomCognetivity Ltd., London, United KingdomDepartment of Stem Cells and Developmental Biology, Cell Science Research Centre, Royan Institute for Stem Cell Biology and Technology, ACECR, Tehran, IranObjectivesThe aim of this study was to develop a comprehensive economic evaluation of the integrated cognitive assessment (ICA) tool compared with standard cognitive tests when used for dementia screening in primary care and for initial patient triage in memory clinics.MethodsICA was compared with standard of care comprising a mixture of cognitive assessment tools over a lifetime horizon and employing the UK health and social care perspective. The model combined a decision tree to capture the initial outcomes of the cognitive testing with a Markov structure that estimated long-term outcomes of people with dementia. Quality of life outcomes were quantified using quality-adjusted life years (QALYs), and the economic benefits were assessed using net monetary benefit (NMB). Both costs and QALYs were discounted at 3.5% per annum and cost-effectiveness was assessed using a threshold of £20,000 per QALY gained.ResultsICA dominated standard cognitive assessment tools in both the primary care and memory clinic settings. Introduction of the ICA tool was estimated to result in a lifetime cost saving of approximately £123 and £226 per person in primary care and memory clinics, respectively. QALY gains associated with early diagnosis were modest (0.0016 in primary care and 0.0027 in memory clinic). The net monetary benefit (NMB) of ICA introduction was estimated at £154 in primary care and £281 in the memory clinic settings.ConclusionIntroduction of ICA as a tool to screen primary care patients for dementia and perform initial triage in memory clinics could be cost saving to the UK public health and social care payer.https://www.frontiersin.org/articles/10.3389/fpubh.2023.1240901/fullICACognICAdementiacognitive screeningAINational Health Service (NHS)
spellingShingle Judith Shore
Chris Kalafatis
Chris Kalafatis
Angela Stainthorpe
Mohammad Hadi Modarres
Seyed-Mahdi Khaligh-Razavi
Seyed-Mahdi Khaligh-Razavi
Health economic analysis of the integrated cognitive assessment tool to aid dementia diagnosis in the United Kingdom
Frontiers in Public Health
ICA
CognICA
dementia
cognitive screening
AI
National Health Service (NHS)
title Health economic analysis of the integrated cognitive assessment tool to aid dementia diagnosis in the United Kingdom
title_full Health economic analysis of the integrated cognitive assessment tool to aid dementia diagnosis in the United Kingdom
title_fullStr Health economic analysis of the integrated cognitive assessment tool to aid dementia diagnosis in the United Kingdom
title_full_unstemmed Health economic analysis of the integrated cognitive assessment tool to aid dementia diagnosis in the United Kingdom
title_short Health economic analysis of the integrated cognitive assessment tool to aid dementia diagnosis in the United Kingdom
title_sort health economic analysis of the integrated cognitive assessment tool to aid dementia diagnosis in the united kingdom
topic ICA
CognICA
dementia
cognitive screening
AI
National Health Service (NHS)
url https://www.frontiersin.org/articles/10.3389/fpubh.2023.1240901/full
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