Antimicrobial susceptibility and biofilm production among Staphylococcus and Candida species
Background: Biofilms are surface-attached groups of microbial cells that are embedded in an extracellular matrix. One of the main features of biofilms is their resistance to antimicrobial drugs; therefore, the biofilm-based infections are extremely difficult to treat. This study aimed to investigat...
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| Format: | Article |
| Language: | English |
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Scientific Medical Association of Moldova
2020-03-01
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| Series: | The Moldovan Medical Journal |
| Subjects: | |
| Online Access: | http://moldmedjournal.md/wp-content/uploads/2020/03/moldovan-med-j-2020-63-1-balan-et-al-full-text.pdf |
| _version_ | 1818677035732566016 |
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| author | Greta Balan Olga Burduniuc |
| author_facet | Greta Balan Olga Burduniuc |
| author_sort | Greta Balan |
| collection | DOAJ |
| description | Background: Biofilms are surface-attached groups of microbial cells that are embedded in an extracellular matrix. One of the main features of biofilms is
their resistance to antimicrobial drugs; therefore, the biofilm-based infections are extremely difficult to treat. This study aimed to investigate the biofilmforming capacity of Staphylococcus spp. and Candida spp. strains isolated from collected clinical samples, as well as to assess their antibiotic susceptibility.
Material and methods: The study was conducted on 134 strains of Staphylococcus spp. and 147 strains of Candida spp. isolated from various clinical
specimens. Both biofilm formation and antibiotic susceptibility of the isolated strains were studied using contemporary standardized microbiological
methods.
Results: The results of the study showed a high biofilm-forming capacity among the clinical strains of Staphylococcus spp. and Candida spp., as well as a
higher level of antibiotic resistance in biofilm-producing strains compared to biofilm non-producing ones.
Conclusions: The high rates of antibiotic resistance and biofilm-forming capacity of strains represent a major public health challenge. The study showed
a strong correlation between biofilm formation and antimicrobial resistance patterns. |
| first_indexed | 2024-12-17T08:52:58Z |
| format | Article |
| id | doaj.art-b768b9bd569d4462bcb0019203a60177 |
| institution | Directory Open Access Journal |
| issn | 2537-6373 2537-6381 |
| language | English |
| last_indexed | 2024-12-17T08:52:58Z |
| publishDate | 2020-03-01 |
| publisher | Scientific Medical Association of Moldova |
| record_format | Article |
| series | The Moldovan Medical Journal |
| spelling | doaj.art-b768b9bd569d4462bcb0019203a601772022-12-21T21:56:01ZengScientific Medical Association of MoldovaThe Moldovan Medical Journal2537-63732537-63812020-03-016313710.5281/zenodo.3685641Antimicrobial susceptibility and biofilm production among Staphylococcus and Candida speciesGreta Balan0https://orcid.org/0000-0003-3704-3584Olga Burduniuc1https://orcid.org/0000-0002-6944-0800Department of Microbiology and Immunology, Nicolae Testemitsanu State University of Medicine and Pharmacy, Chisinau, the Republic of MoldovaDepartment of Microbiology and Immunology, Nicolae Testemitsanu State University of Medicine and Pharmacy, Chisinau, the Republic of MoldovaBackground: Biofilms are surface-attached groups of microbial cells that are embedded in an extracellular matrix. One of the main features of biofilms is their resistance to antimicrobial drugs; therefore, the biofilm-based infections are extremely difficult to treat. This study aimed to investigate the biofilmforming capacity of Staphylococcus spp. and Candida spp. strains isolated from collected clinical samples, as well as to assess their antibiotic susceptibility. Material and methods: The study was conducted on 134 strains of Staphylococcus spp. and 147 strains of Candida spp. isolated from various clinical specimens. Both biofilm formation and antibiotic susceptibility of the isolated strains were studied using contemporary standardized microbiological methods. Results: The results of the study showed a high biofilm-forming capacity among the clinical strains of Staphylococcus spp. and Candida spp., as well as a higher level of antibiotic resistance in biofilm-producing strains compared to biofilm non-producing ones. Conclusions: The high rates of antibiotic resistance and biofilm-forming capacity of strains represent a major public health challenge. The study showed a strong correlation between biofilm formation and antimicrobial resistance patterns.http://moldmedjournal.md/wp-content/uploads/2020/03/moldovan-med-j-2020-63-1-balan-et-al-full-text.pdfstaphylococcus spp.candida spp.biofilm formationantimicrobial resistance |
| spellingShingle | Greta Balan Olga Burduniuc Antimicrobial susceptibility and biofilm production among Staphylococcus and Candida species The Moldovan Medical Journal staphylococcus spp. candida spp. biofilm formation antimicrobial resistance |
| title | Antimicrobial susceptibility and biofilm production among Staphylococcus and Candida species |
| title_full | Antimicrobial susceptibility and biofilm production among Staphylococcus and Candida species |
| title_fullStr | Antimicrobial susceptibility and biofilm production among Staphylococcus and Candida species |
| title_full_unstemmed | Antimicrobial susceptibility and biofilm production among Staphylococcus and Candida species |
| title_short | Antimicrobial susceptibility and biofilm production among Staphylococcus and Candida species |
| title_sort | antimicrobial susceptibility and biofilm production among staphylococcus and candida species |
| topic | staphylococcus spp. candida spp. biofilm formation antimicrobial resistance |
| url | http://moldmedjournal.md/wp-content/uploads/2020/03/moldovan-med-j-2020-63-1-balan-et-al-full-text.pdf |
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