MoCA Domain-Specific Pattern of Cognitive Impairment in Stroke Patients Attending Intensive Inpatient Rehabilitation: A Prospective Study
A domain-specific perspective to cognitive functioning in stroke patients may predict their cognitive recovery over time and target stroke rehabilitation intervention. However, data about domain-specific cognitive impairment after stroke are still scarce. This study prospectively investigated the do...
| Main Authors: | , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2024-01-01
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| Series: | Behavioral Sciences |
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| Online Access: | https://www.mdpi.com/2076-328X/14/1/42 |
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| author | Benedetta Basagni Serena Malloggi Cristina Polito Leonardo Pellicciari Silvia Campagnini Silvia Pancani Andrea Mannini Paola Gemignani Emilia Salvadori Sara Marignani Fabio Giovannelli Maria Pia Viggiano Bahia Hakiki Antonello Grippo Claudio Macchi Francesca Cecchi |
| author_facet | Benedetta Basagni Serena Malloggi Cristina Polito Leonardo Pellicciari Silvia Campagnini Silvia Pancani Andrea Mannini Paola Gemignani Emilia Salvadori Sara Marignani Fabio Giovannelli Maria Pia Viggiano Bahia Hakiki Antonello Grippo Claudio Macchi Francesca Cecchi |
| author_sort | Benedetta Basagni |
| collection | DOAJ |
| description | A domain-specific perspective to cognitive functioning in stroke patients may predict their cognitive recovery over time and target stroke rehabilitation intervention. However, data about domain-specific cognitive impairment after stroke are still scarce. This study prospectively investigated the domain-specific pattern of cognitive impairments, using the classification proposed by the Montreal Cognitive Assessment (MoCA), in a cohort of 49 stroke patients at admission (T0), discharge (T1), and six-month follow-up (T2) from subacute intensive rehabilitation. The predictive value of T0 cognitive domains cognitive impairment at T1 and T2 was also investigated. Patients’ cognitive functioning at T0, T1, and T2 was assessed through the MoCA domains for executive functioning, attention, language, visuospatial, orientation, and memory. Different evolutionary trends of cognitive domain impairments emerged across time-points. Patients’ impairments in all domains decreased from T0 to T1. Attention and executive impairments decreased from T0 to T2 (42.9% and 26.5% to 10.2% and 18.4%, respectively). Conversely, altered visuospatial, language, and orientation increased between T1 and T2 (16.3%, 36.7%, and 40.8%, respectively). Additionally, patients’ global cognitive functioning at T1 was predicted by the language and executive domains in a subacute phase (<i>p</i> = 0.031 and <i>p</i> = 0.001, respectively), while in the long term, only attention (<i>p</i> = 0.043) and executive (<i>p</i> = 0.019) domains intervened. Overall, these results confirm the importance of a domain-specific approach to target cognitive recovery across time in stroke patients. |
| first_indexed | 2024-03-08T11:05:39Z |
| format | Article |
| id | doaj.art-b76b62a282f246a9bdaa91535c235955 |
| institution | Directory Open Access Journal |
| issn | 2076-328X |
| language | English |
| last_indexed | 2024-03-08T11:05:39Z |
| publishDate | 2024-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Behavioral Sciences |
| spelling | doaj.art-b76b62a282f246a9bdaa91535c2359552024-01-26T15:05:52ZengMDPI AGBehavioral Sciences2076-328X2024-01-011414210.3390/bs14010042MoCA Domain-Specific Pattern of Cognitive Impairment in Stroke Patients Attending Intensive Inpatient Rehabilitation: A Prospective StudyBenedetta Basagni0Serena Malloggi1Cristina Polito2Leonardo Pellicciari3Silvia Campagnini4Silvia Pancani5Andrea Mannini6Paola Gemignani7Emilia Salvadori8Sara Marignani9Fabio Giovannelli10Maria Pia Viggiano11Bahia Hakiki12Antonello Grippo13Claudio Macchi14Francesca Cecchi15IRCCS Fondazione Don Carlo Gnocchi, 50143 Firenze, ItalyIRCCS Fondazione Don Carlo Gnocchi, 50143 Firenze, ItalyIRCCS Fondazione Don Carlo Gnocchi, 50143 Firenze, ItalyIRCCS Fondazione Don Carlo Gnocchi, 50143 Firenze, ItalyIRCCS Fondazione Don Carlo Gnocchi, 50143 Firenze, ItalyIRCCS Fondazione Don Carlo Gnocchi, 50143 Firenze, ItalyIRCCS Fondazione Don Carlo Gnocchi, 50143 Firenze, ItalyIRCCS Fondazione Don Carlo Gnocchi, 50143 Firenze, ItalyIRCCS Fondazione Don Carlo Gnocchi, 50143 Firenze, ItalyIRCCS Fondazione Don Carlo Gnocchi, 50143 Firenze, ItalyDepartment of NEUROFARBA, University of Florence, 50143 Firenze, ItalyDepartment of NEUROFARBA, University of Florence, 50143 Firenze, ItalyIRCCS Fondazione Don Carlo Gnocchi, 50143 Firenze, ItalyIRCCS Fondazione Don Carlo Gnocchi, 50143 Firenze, ItalyIRCCS Fondazione Don Carlo Gnocchi, 50143 Firenze, ItalyIRCCS Fondazione Don Carlo Gnocchi, 50143 Firenze, ItalyA domain-specific perspective to cognitive functioning in stroke patients may predict their cognitive recovery over time and target stroke rehabilitation intervention. However, data about domain-specific cognitive impairment after stroke are still scarce. This study prospectively investigated the domain-specific pattern of cognitive impairments, using the classification proposed by the Montreal Cognitive Assessment (MoCA), in a cohort of 49 stroke patients at admission (T0), discharge (T1), and six-month follow-up (T2) from subacute intensive rehabilitation. The predictive value of T0 cognitive domains cognitive impairment at T1 and T2 was also investigated. Patients’ cognitive functioning at T0, T1, and T2 was assessed through the MoCA domains for executive functioning, attention, language, visuospatial, orientation, and memory. Different evolutionary trends of cognitive domain impairments emerged across time-points. Patients’ impairments in all domains decreased from T0 to T1. Attention and executive impairments decreased from T0 to T2 (42.9% and 26.5% to 10.2% and 18.4%, respectively). Conversely, altered visuospatial, language, and orientation increased between T1 and T2 (16.3%, 36.7%, and 40.8%, respectively). Additionally, patients’ global cognitive functioning at T1 was predicted by the language and executive domains in a subacute phase (<i>p</i> = 0.031 and <i>p</i> = 0.001, respectively), while in the long term, only attention (<i>p</i> = 0.043) and executive (<i>p</i> = 0.019) domains intervened. Overall, these results confirm the importance of a domain-specific approach to target cognitive recovery across time in stroke patients.https://www.mdpi.com/2076-328X/14/1/42cognitioncognitive domainsMontreal Cognitive Assessmentpost-stroke cognitive impairmentprognosisrehabilitation |
| spellingShingle | Benedetta Basagni Serena Malloggi Cristina Polito Leonardo Pellicciari Silvia Campagnini Silvia Pancani Andrea Mannini Paola Gemignani Emilia Salvadori Sara Marignani Fabio Giovannelli Maria Pia Viggiano Bahia Hakiki Antonello Grippo Claudio Macchi Francesca Cecchi MoCA Domain-Specific Pattern of Cognitive Impairment in Stroke Patients Attending Intensive Inpatient Rehabilitation: A Prospective Study Behavioral Sciences cognition cognitive domains Montreal Cognitive Assessment post-stroke cognitive impairment prognosis rehabilitation |
| title | MoCA Domain-Specific Pattern of Cognitive Impairment in Stroke Patients Attending Intensive Inpatient Rehabilitation: A Prospective Study |
| title_full | MoCA Domain-Specific Pattern of Cognitive Impairment in Stroke Patients Attending Intensive Inpatient Rehabilitation: A Prospective Study |
| title_fullStr | MoCA Domain-Specific Pattern of Cognitive Impairment in Stroke Patients Attending Intensive Inpatient Rehabilitation: A Prospective Study |
| title_full_unstemmed | MoCA Domain-Specific Pattern of Cognitive Impairment in Stroke Patients Attending Intensive Inpatient Rehabilitation: A Prospective Study |
| title_short | MoCA Domain-Specific Pattern of Cognitive Impairment in Stroke Patients Attending Intensive Inpatient Rehabilitation: A Prospective Study |
| title_sort | moca domain specific pattern of cognitive impairment in stroke patients attending intensive inpatient rehabilitation a prospective study |
| topic | cognition cognitive domains Montreal Cognitive Assessment post-stroke cognitive impairment prognosis rehabilitation |
| url | https://www.mdpi.com/2076-328X/14/1/42 |
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