Melanin is a plenteous bioactive phenolic compound in date fruits (Phoenix dactylifera L.)
Abstract Date palm fruits (Phoenix dactylifera L.) were found to contain high levels of allomelanin (1.2–5.1%). The melanin is localized in the tanniferous cells between the inner and outer mesocarp tissues of the fruit. The melanin, extracted with 2 M sodium hydroxide, consisted of amorphous graphe...
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2022-04-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-022-10546-9 |
| _version_ | 1817989083455029248 |
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| author | Muneeba Zubair Alam Tholkappiyan Ramachandran Asha Antony Fathalla Hamed Mutamed Ayyash Afaf Kamal-Eldin |
| author_facet | Muneeba Zubair Alam Tholkappiyan Ramachandran Asha Antony Fathalla Hamed Mutamed Ayyash Afaf Kamal-Eldin |
| author_sort | Muneeba Zubair Alam |
| collection | DOAJ |
| description | Abstract Date palm fruits (Phoenix dactylifera L.) were found to contain high levels of allomelanin (1.2–5.1%). The melanin is localized in the tanniferous cells between the inner and outer mesocarp tissues of the fruit. The melanin, extracted with 2 M sodium hydroxide, consisted of amorphous graphene-like granular structures of irregular shape and variable size. The date fruit melanin mainly comprises carbon (64.6%) and oxygen (30.6) but no nitrogen, and was thermally stable. It has radical scavenging (63.6–75.1 IC50, µg/mL), antimicrobial (250–1000 µg/mL), hypoglycemic (51.8–58.2%), and angiotensin-converting-enzyme inhibitory (65.8%) effects. The high level of melanin in date fruits highlights the importance of investigating its dietary intake and its impact on nutrition. This study also suggests that date fruit melanin can be a functional ingredient in foods, food packages, pharmaceuticals, and cosmetics. |
| first_indexed | 2024-04-14T00:42:43Z |
| format | Article |
| id | doaj.art-b76be67f5de74d4f87b9145459c677b9 |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-04-14T00:42:43Z |
| publishDate | 2022-04-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj.art-b76be67f5de74d4f87b9145459c677b92022-12-22T02:22:08ZengNature PortfolioScientific Reports2045-23222022-04-0112111210.1038/s41598-022-10546-9Melanin is a plenteous bioactive phenolic compound in date fruits (Phoenix dactylifera L.)Muneeba Zubair Alam0Tholkappiyan Ramachandran1Asha Antony2Fathalla Hamed3Mutamed Ayyash4Afaf Kamal-Eldin5Department of Food Science, College of Agriculture and Veterinary Medicine, United Arab Emirates UniversityDepartment of Physics, College of Science and National Water and Energy Center United Arab, Emirates UniversityDepartment of Veterinary Medicine, College of Agriculture and Veterinary Medicine, United Arab Emirates UniversityDepartment of Physics, College of Science and National Water and Energy Center United Arab, Emirates UniversityDepartment of Food Science, College of Agriculture and Veterinary Medicine, United Arab Emirates UniversityDepartment of Food Science, College of Agriculture and Veterinary Medicine, United Arab Emirates UniversityAbstract Date palm fruits (Phoenix dactylifera L.) were found to contain high levels of allomelanin (1.2–5.1%). The melanin is localized in the tanniferous cells between the inner and outer mesocarp tissues of the fruit. The melanin, extracted with 2 M sodium hydroxide, consisted of amorphous graphene-like granular structures of irregular shape and variable size. The date fruit melanin mainly comprises carbon (64.6%) and oxygen (30.6) but no nitrogen, and was thermally stable. It has radical scavenging (63.6–75.1 IC50, µg/mL), antimicrobial (250–1000 µg/mL), hypoglycemic (51.8–58.2%), and angiotensin-converting-enzyme inhibitory (65.8%) effects. The high level of melanin in date fruits highlights the importance of investigating its dietary intake and its impact on nutrition. This study also suggests that date fruit melanin can be a functional ingredient in foods, food packages, pharmaceuticals, and cosmetics.https://doi.org/10.1038/s41598-022-10546-9 |
| spellingShingle | Muneeba Zubair Alam Tholkappiyan Ramachandran Asha Antony Fathalla Hamed Mutamed Ayyash Afaf Kamal-Eldin Melanin is a plenteous bioactive phenolic compound in date fruits (Phoenix dactylifera L.) Scientific Reports |
| title | Melanin is a plenteous bioactive phenolic compound in date fruits (Phoenix dactylifera L.) |
| title_full | Melanin is a plenteous bioactive phenolic compound in date fruits (Phoenix dactylifera L.) |
| title_fullStr | Melanin is a plenteous bioactive phenolic compound in date fruits (Phoenix dactylifera L.) |
| title_full_unstemmed | Melanin is a plenteous bioactive phenolic compound in date fruits (Phoenix dactylifera L.) |
| title_short | Melanin is a plenteous bioactive phenolic compound in date fruits (Phoenix dactylifera L.) |
| title_sort | melanin is a plenteous bioactive phenolic compound in date fruits phoenix dactylifera l |
| url | https://doi.org/10.1038/s41598-022-10546-9 |
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