Natural killer cells kill extracellular Pseudomonas aeruginosa using contact-dependent release of granzymes B and H.

Natural killer cells kill extracellular Pseudomonas aeruginosa using contact-dependent release of granzymes B and H.

Pseudomonas aeruginosa is an opportunistic pathogen that often infects individuals with the genetic disease cystic fibrosis, and contributes to airway blockage and loss of lung function. Natural killer (NK) cells are cytotoxic, granular lymphocytes that are part of the innate immune system. NK cell...

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Bibliographic Details
Main Authors: David D Feehan, Khusraw Jamil, Maria J Polyak, Henry Ogbomo, Mark Hasell, Shu Shun Li, Richard F Xiang, Michael Parkins, Joseph A Trapani, Joe J Harrison, Christopher H Mody
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-02-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1010325

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