Effect of Quercetin on the Expression and Growth of caspase-3 in Lung Adenocarcinoma Cancer Cell Line A549
Background and objective To study the influence of Quercetin in the expression of caspase-3 in Lung Adenocarcinoma Cancer cell line A549. Methods The mRNA expression of caspase-3 in A549 Cells was detected by RT-PCR , and the protein expression was detected by Western blot. Results The mRNA and prot...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | zho |
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Chinese Anti-Cancer Association; Chinese Antituberculosis Association
2008-04-01
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| Series: | Chinese Journal of Lung Cancer |
| Subjects: | |
| Online Access: | http://www.lungca.org/index.php?journal=01&page=article&op=view&path%5B%5D=10.3779%2Fj.issn.1009-3419.2008.02.002&path%5B%5D=48 |
| _version_ | 1818564443381956608 |
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| author | Jie ZHANG Hong FAN Yonggang ZHANG Chunsheng WEN Binwu YING |
| author_facet | Jie ZHANG Hong FAN Yonggang ZHANG Chunsheng WEN Binwu YING |
| author_sort | Jie ZHANG |
| collection | DOAJ |
| description | Background and objective To study the influence of Quercetin in the expression of caspase-3 in Lung Adenocarcinoma Cancer cell line A549. Methods The mRNA expression of caspase-3 in A549 Cells was detected by RT-PCR , and the protein expression was detected by Western blot. Results The mRNA and protein expressions of caspase-3 was enhanced by Quercetin in dose-and time-dependent manners. Conclusion The enhancement effects of Quercetin on caspase-3 in A549 cells may provide promising therapy of tumor. |
| first_indexed | 2024-12-14T01:28:58Z |
| format | Article |
| id | doaj.art-b778d1de96604910b64258f9e63675e7 |
| institution | Directory Open Access Journal |
| issn | 1009-3419 1999-6187 |
| language | zho |
| last_indexed | 2024-12-14T01:28:58Z |
| publishDate | 2008-04-01 |
| publisher | Chinese Anti-Cancer Association; Chinese Antituberculosis Association |
| record_format | Article |
| series | Chinese Journal of Lung Cancer |
| spelling | doaj.art-b778d1de96604910b64258f9e63675e72022-12-21T23:22:05ZzhoChinese Anti-Cancer Association; Chinese Antituberculosis AssociationChinese Journal of Lung Cancer1009-34191999-61872008-04-01112194197Effect of Quercetin on the Expression and Growth of caspase-3 in Lung Adenocarcinoma Cancer Cell Line A549Jie ZHANGHong FANYonggang ZHANGChunsheng WENBinwu YINGBackground and objective To study the influence of Quercetin in the expression of caspase-3 in Lung Adenocarcinoma Cancer cell line A549. Methods The mRNA expression of caspase-3 in A549 Cells was detected by RT-PCR , and the protein expression was detected by Western blot. Results The mRNA and protein expressions of caspase-3 was enhanced by Quercetin in dose-and time-dependent manners. Conclusion The enhancement effects of Quercetin on caspase-3 in A549 cells may provide promising therapy of tumor.http://www.lungca.org/index.php?journal=01&page=article&op=view&path%5B%5D=10.3779%2Fj.issn.1009-3419.2008.02.002&path%5B%5D=48QuercetinLung neoplasmsCaspase-3Apoptosis |
| spellingShingle | Jie ZHANG Hong FAN Yonggang ZHANG Chunsheng WEN Binwu YING Effect of Quercetin on the Expression and Growth of caspase-3 in Lung Adenocarcinoma Cancer Cell Line A549 Chinese Journal of Lung Cancer Quercetin Lung neoplasms Caspase-3 Apoptosis |
| title | Effect of Quercetin on the Expression and Growth of caspase-3 in Lung Adenocarcinoma Cancer Cell Line A549 |
| title_full | Effect of Quercetin on the Expression and Growth of caspase-3 in Lung Adenocarcinoma Cancer Cell Line A549 |
| title_fullStr | Effect of Quercetin on the Expression and Growth of caspase-3 in Lung Adenocarcinoma Cancer Cell Line A549 |
| title_full_unstemmed | Effect of Quercetin on the Expression and Growth of caspase-3 in Lung Adenocarcinoma Cancer Cell Line A549 |
| title_short | Effect of Quercetin on the Expression and Growth of caspase-3 in Lung Adenocarcinoma Cancer Cell Line A549 |
| title_sort | effect of quercetin on the expression and growth of caspase 3 in lung adenocarcinoma cancer cell line a549 |
| topic | Quercetin Lung neoplasms Caspase-3 Apoptosis |
| url | http://www.lungca.org/index.php?journal=01&page=article&op=view&path%5B%5D=10.3779%2Fj.issn.1009-3419.2008.02.002&path%5B%5D=48 |
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