Effects of Steroids on Edema and Ecchymosis in Rhinoplasty

A randomized, prospective double-blind study with placebo control was planned to determine the effects of a single-dose dexamethasone in reducing postoperative edema and ecchymosis after rhinoplasty. Fifty-six consecutive patients who underwent rhinoplasty with hump removal and lateral osteotomies w...

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Main Authors: Ferhat Erişir, Fatih Öktem, Ender İnci
Format: Article
Language:English
Published: Galenos Yayincilik 2001-09-01
Series:Turkish Archives of Otorhinolaryngology
Subjects:
Online Access: http://turkarchotolaryngol.net/archives/archive-detail/article-preview/effects-of-steroids-on-edema-and-ecchymosis-in-rhi/43833
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author Ferhat Erişir
Fatih Öktem
Ender İnci
author_facet Ferhat Erişir
Fatih Öktem
Ender İnci
author_sort Ferhat Erişir
collection DOAJ
description A randomized, prospective double-blind study with placebo control was planned to determine the effects of a single-dose dexamethasone in reducing postoperative edema and ecchymosis after rhinoplasty. Fifty-six consecutive patients who underwent rhinoplasty with hump removal and lateral osteotomies were enrolled in this study. Thirty patients received 10 mg of dexamethasone intravenously before surgery and twenty-six patients received placebo. Postoperative scoring of edema and ecchymosis was begun approximately 24 hours after surgery. All patients were operated by the authors. A 4-point scale was used to assess the extent of periorbital edema and ecchymosis 24 hours postoperatively. A single-dose of 10 mg of dexamethasone intravenously reduced postoperative edema and ecchymosis significantly. The first two days differences between the steroid and placebo groups for edema and ecchymosis were clinically and statistically significant (p < 0.05). This study showed a statistically significant benefit of steroids when compared to placebo in decreasing edema and ecchymosis in rhinoplasty. However, the effect of dexamethasone has disappeared after the first two days, and its use did not shorten the recovery. No complications were attributed to the administration of dexamethasone.
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spelling doaj.art-b77b31b0ffab41b688c56c52ec41f9792023-02-15T16:11:20ZengGalenos YayincilikTurkish Archives of Otorhinolaryngology2667-74742001-09-0139317117513049054Effects of Steroids on Edema and Ecchymosis in RhinoplastyFerhat Erişir0Fatih Öktem1Ender İnci2 Cerrahpaşa School of Medicine, Istanbul University, ENT Department Cerrahpaşa School of Medicine, Istanbul University, ENT Department Cerrahpaşa School of Medicine, Istanbul University, ENT Department A randomized, prospective double-blind study with placebo control was planned to determine the effects of a single-dose dexamethasone in reducing postoperative edema and ecchymosis after rhinoplasty. Fifty-six consecutive patients who underwent rhinoplasty with hump removal and lateral osteotomies were enrolled in this study. Thirty patients received 10 mg of dexamethasone intravenously before surgery and twenty-six patients received placebo. Postoperative scoring of edema and ecchymosis was begun approximately 24 hours after surgery. All patients were operated by the authors. A 4-point scale was used to assess the extent of periorbital edema and ecchymosis 24 hours postoperatively. A single-dose of 10 mg of dexamethasone intravenously reduced postoperative edema and ecchymosis significantly. The first two days differences between the steroid and placebo groups for edema and ecchymosis were clinically and statistically significant (p < 0.05). This study showed a statistically significant benefit of steroids when compared to placebo in decreasing edema and ecchymosis in rhinoplasty. However, the effect of dexamethasone has disappeared after the first two days, and its use did not shorten the recovery. No complications were attributed to the administration of dexamethasone. http://turkarchotolaryngol.net/archives/archive-detail/article-preview/effects-of-steroids-on-edema-and-ecchymosis-in-rhi/43833 rhinoplastysteroidslateral osteotomiesedema.
spellingShingle Ferhat Erişir
Fatih Öktem
Ender İnci
Effects of Steroids on Edema and Ecchymosis in Rhinoplasty
Turkish Archives of Otorhinolaryngology
rhinoplasty
steroids
lateral osteotomies
edema.
title Effects of Steroids on Edema and Ecchymosis in Rhinoplasty
title_full Effects of Steroids on Edema and Ecchymosis in Rhinoplasty
title_fullStr Effects of Steroids on Edema and Ecchymosis in Rhinoplasty
title_full_unstemmed Effects of Steroids on Edema and Ecchymosis in Rhinoplasty
title_short Effects of Steroids on Edema and Ecchymosis in Rhinoplasty
title_sort effects of steroids on edema and ecchymosis in rhinoplasty
topic rhinoplasty
steroids
lateral osteotomies
edema.
url http://turkarchotolaryngol.net/archives/archive-detail/article-preview/effects-of-steroids-on-edema-and-ecchymosis-in-rhi/43833
work_keys_str_mv AT ferhaterisir effectsofsteroidsonedemaandecchymosisinrhinoplasty
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AT enderinci effectsofsteroidsonedemaandecchymosisinrhinoplasty