Structural alteration of DNA induced by viral protein R of HIV-1 triggers the DNA damage response
Abstract Background Viral protein R (Vpr) is an accessory protein of HIV-1, which is potentially involved in the infection of macrophages and the induction of the ataxia-telangiectasia and Rad3-related protein (ATR)-mediated DNA damage response (DDR). It was recently proposed that the SLX4 complex o...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2018-01-01
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| Series: | Retrovirology |
| Online Access: | http://link.springer.com/article/10.1186/s12977-018-0391-8 |