Curcumin-dependent phenotypic transformation of microglia mediates resistance to pseudorabies-induced encephalitis

Curcumin-dependent phenotypic transformation of microglia mediates resistance to pseudorabies-induced encephalitis

Abstract Pseudorabies virus (PRV) causes viral encephalitis, a devastating disease with high mortality worldwide. Curcumin (CUR) can reduce inflammatory damage by altering the phenotype of microglia; however, whether and how these changes mediate resistance to PRV-induced encephalitis is still uncle...

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Bibliographic Details
Main Authors: Luqiu Feng, Guodong Luo, Yuhang Li, Chen Zhang, Yuxuan Liu, Yanqing Liu, Hongyue Chen, Daoling He, Yan Zhu, Ling Gan
Format: Article
Language:English
Published: BMC 2023-03-01
Series:Veterinary Research
Subjects:
BV2
Curcumin
PRV
phenotype
AMPK
mitochondria
Online Access:https://doi.org/10.1186/s13567-023-01149-x

Internet

https://doi.org/10.1186/s13567-023-01149-x

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