Relationships of Gut Microbiota Composition, Short-Chain Fatty Acids and Polyamines with the Pathological Response to Neoadjuvant Radiochemotherapy in Colorectal Cancer Patients

Relationships of Gut Microbiota Composition, Short-Chain Fatty Acids and Polyamines with the Pathological Response to Neoadjuvant Radiochemotherapy in Colorectal Cancer Patients

Emerging evidence has suggested that dysbiosis of the gut microbiota may influence the drug efficacy of colorectal cancer (CRC) patients during cancer treatment by modulating drug metabolism and the host immune response. Moreover, gut microbiota can produce metabolites that may influence tumor proli...

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Bibliographic Details
Main Authors: Lidia Sánchez-Alcoholado, Aurora Laborda-Illanes, Ana Otero, Rafael Ordóñez, Alicia González-González, Isaac Plaza-Andrades, Bruno Ramos-Molina, Jaime Gómez-Millán, María Isabel Queipo-Ortuño
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:International Journal of Molecular Sciences
Subjects:
colorectal cancer
gut microbiota
SCFAs
gut permeability
radiochemotherapy
treatment outcome
Online Access:https://www.mdpi.com/1422-0067/22/17/9549

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