Osteoporosis and diabetes mellitus: a modern viewpoint
The interrelationship between diabetes mellitus (DM) and bone disorder is still not fully understood. Whereas type 1 diabetes mellitus (T1DM) is characterized by decrease in bone density, a number of studies failed to discover such phenomenon in type 2 diabetes mel- litus (T2DM), ? or even uncovered...
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| Format: | Article |
| Language: | English |
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Endocrinology Research Centre
2013-03-01
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| Series: | Сахарный диабет |
| Subjects: | |
| Online Access: | https://www.dia-endojournals.ru/jour/article/view/3598 |
| _version_ | 1797255234400026624 |
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| author | Natalya Alexandrovna Molitvoslovova Gagik Radikovich Galstyan |
| author_facet | Natalya Alexandrovna Molitvoslovova Gagik Radikovich Galstyan |
| author_sort | Natalya Alexandrovna Molitvoslovova |
| collection | DOAJ |
| description | The interrelationship between diabetes mellitus (DM) and bone disorder is still not fully understood. Whereas type 1 diabetes mellitus (T1DM) is characterized by decrease in bone density, a number of studies failed to discover such phenomenon in type 2 diabetes mel- litus (T2DM), ? or even uncovered some evidence for higher density, as measured against groups of control. At the very same time both types of DM are associated with elevated risk of bone fracture, which points out at some deterioration of bone tissue ?quality?. Current article discusses various mechanisms of bone damaging in DM, as well as possible causes for difference in the severity of bone disorders, known between the two types of DM. Regarding higher risk of foot fracture in patients with DM, we specifically address distal polyneuropathy as a plausible factor for bone tissue deterioration. |
| first_indexed | 2024-03-08T15:21:39Z |
| format | Article |
| id | doaj.art-b795c459e5064604823391c089a2480c |
| institution | Directory Open Access Journal |
| issn | 2072-0351 2072-0378 |
| language | English |
| last_indexed | 2024-04-24T22:02:37Z |
| publishDate | 2013-03-01 |
| publisher | Endocrinology Research Centre |
| record_format | Article |
| series | Сахарный диабет |
| spelling | doaj.art-b795c459e5064604823391c089a2480c2024-03-20T11:47:58ZengEndocrinology Research CentreСахарный диабет2072-03512072-03782013-03-01161576210.14341/2072-0351-35983568Osteoporosis and diabetes mellitus: a modern viewpointNatalya Alexandrovna Molitvoslovova0Gagik Radikovich Galstyan1Endocrinology Research Centre, MoscowEndocrinology Research Centre, MoscowThe interrelationship between diabetes mellitus (DM) and bone disorder is still not fully understood. Whereas type 1 diabetes mellitus (T1DM) is characterized by decrease in bone density, a number of studies failed to discover such phenomenon in type 2 diabetes mel- litus (T2DM), ? or even uncovered some evidence for higher density, as measured against groups of control. At the very same time both types of DM are associated with elevated risk of bone fracture, which points out at some deterioration of bone tissue ?quality?. Current article discusses various mechanisms of bone damaging in DM, as well as possible causes for difference in the severity of bone disorders, known between the two types of DM. Regarding higher risk of foot fracture in patients with DM, we specifically address distal polyneuropathy as a plausible factor for bone tissue deterioration.https://www.dia-endojournals.ru/jour/article/view/3598osteoporosisdiabetes mellitusdistal diabetic neuropathy |
| spellingShingle | Natalya Alexandrovna Molitvoslovova Gagik Radikovich Galstyan Osteoporosis and diabetes mellitus: a modern viewpoint Сахарный диабет osteoporosis diabetes mellitus distal diabetic neuropathy |
| title | Osteoporosis and diabetes mellitus: a modern viewpoint |
| title_full | Osteoporosis and diabetes mellitus: a modern viewpoint |
| title_fullStr | Osteoporosis and diabetes mellitus: a modern viewpoint |
| title_full_unstemmed | Osteoporosis and diabetes mellitus: a modern viewpoint |
| title_short | Osteoporosis and diabetes mellitus: a modern viewpoint |
| title_sort | osteoporosis and diabetes mellitus a modern viewpoint |
| topic | osteoporosis diabetes mellitus distal diabetic neuropathy |
| url | https://www.dia-endojournals.ru/jour/article/view/3598 |
| work_keys_str_mv | AT natalyaalexandrovnamolitvoslovova osteoporosisanddiabetesmellitusamodernviewpoint AT gagikradikovichgalstyan osteoporosisanddiabetesmellitusamodernviewpoint |