Advances in Clinical Sample Preparation for Identification and Characterization of Bacterial Pathogens Using Metagenomics

Advances in Clinical Sample Preparation for Identification and Characterization of Bacterial Pathogens Using Metagenomics

Whole genome sequencing (WGS) plays an increasing role in communicable disease control through high-resolution outbreak tracing, laboratory surveillance and diagnostics. However, WGS has traditionally relied on microbial culture in order to obtain pathogen specific DNA for sequencing. This has sever...

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Bibliographic Details
Main Authors: Nathan L. Bachmann, Rebecca J. Rockett, Verlaine Joy Timms, Vitali Sintchenko
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-12-01
Series:Frontiers in Public Health
Subjects:
metagenomic
culture-independent genome sequencing
bacterial pathogens
Mycobacterium tuberculosis
public health
Online Access:https://www.frontiersin.org/article/10.3389/fpubh.2018.00363/full

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