Increased Expression of Estrogen Receptor α-36 by Breast Cancer Oncogene IKKε Promotes Growth of ER-Negative Breast Cancer Cells

Increased Expression of Estrogen Receptor α-36 by Breast Cancer Oncogene IKKε Promotes Growth of ER-Negative Breast Cancer Cells

Background/Aims: The expression of estrogen receptor-α (ERα) is one of the most important diagnostic and prognostic factors of breast cancer. Recently, ERα-36 has been identified as a novel variant of ER-α. ERα-36 lacks intrinsic transcription activity and mainly mediates non-genomic estrogen signal...

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Bibliographic Details
Main Authors: Qihong Li, Haiyan Sun, Jingcai Zou, Cheng Ge, Kaitao Yu, Yuan Cao, Quan Hong
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2013-06-01
Series:Cellular Physiology and Biochemistry
Subjects:
IKKε
ER-α36
ER-negative breast cancer
Online Access:http://www.karger.com/Article/FullText/350101

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