Phenolic Profiles, Antioxidant and Anti-Inflammatory Activities of Hydrodistillation Wastewaters from Five Lamiaceae Species
Distillation is the most widely used method to obtain an essential oil from plant material. The biomass used in the process is returned as a solid residue together with variable amounts of water rich in water-soluble compounds, which currently are not addressed to any further application. The scope...
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MDPI AG
2022-11-01
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| Series: | Molecules |
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| Online Access: | https://www.mdpi.com/1420-3049/27/21/7427 |
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| author | Edoardo Napoli Giuseppe Ruberto Alessandra Carrubba Mauro Sarno Claudia Muscarà Antonio Speciale Mariateresa Cristani Francesco Cimino Antonella Saija |
| author_facet | Edoardo Napoli Giuseppe Ruberto Alessandra Carrubba Mauro Sarno Claudia Muscarà Antonio Speciale Mariateresa Cristani Francesco Cimino Antonella Saija |
| author_sort | Edoardo Napoli |
| collection | DOAJ |
| description | Distillation is the most widely used method to obtain an essential oil from plant material. The biomass used in the process is returned as a solid residue together with variable amounts of water rich in water-soluble compounds, which currently are not addressed to any further application. The scope of this work was to evaluate the phytochemical composition of wastewaters coming from hydrodistillation (DWWs) of five aromatic plants belonging to the <i>Lamiaceae</i> family, and to assess their in vitro antioxidant and anti-inflammatory activities. The phenolic profiles of the DWWs were determined by HPLC-DAD and HPLC-ESI/MS. Free radical scavenging ability, oxygen radical antioxidant capacity and superoxide dismutase mimetic activity of the samples under study were measured. Moreover, to investigate the anti-inflammatory activity of the DWWs, an in vitro experimental model of intestinal inflammation was used. The DWW samples’ phytochemical analysis allowed the identification of 37 phenolic compounds, all exhibiting good antioxidant and anti-inflammatory activity. Our study contributes to the knowledge on the polyphenolic composition of the DWWs of five aromatic plants of the Lamiaceae family. The results highlight the presence of compounds with proven biological activity, and therefore of great interest in the pharmaceutical and nutraceutical fields. |
| first_indexed | 2024-03-09T18:48:15Z |
| format | Article |
| id | doaj.art-b7a10e5486434f59a02556dda11a4275 |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-03-09T18:48:15Z |
| publishDate | 2022-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-b7a10e5486434f59a02556dda11a42752023-11-24T06:04:07ZengMDPI AGMolecules1420-30492022-11-012721742710.3390/molecules27217427Phenolic Profiles, Antioxidant and Anti-Inflammatory Activities of Hydrodistillation Wastewaters from Five Lamiaceae SpeciesEdoardo Napoli0Giuseppe Ruberto1Alessandra Carrubba2Mauro Sarno3Claudia Muscarà4Antonio Speciale5Mariateresa Cristani6Francesco Cimino7Antonella Saija8Institute of Biomolecular Chemistry, National Research Council (ICB-CNR), Via P. Gaifami 18, 95126 Catania, ItalyInstitute of Biomolecular Chemistry, National Research Council (ICB-CNR), Via P. Gaifami 18, 95126 Catania, ItalyDepartment of Agricultural, Food and Forest Sciences, University of Palermo, Viale delle Scienze, Build 4, Entr. L, 90128 Palermo, ItalyDepartment of Agricultural, Food and Forest Sciences, University of Palermo, Viale delle Scienze, Build 4, Entr. L, 90128 Palermo, ItalyDepartment of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Viale Ferdinando Stagno D’Alcontres 31, 98166 Messina, ItalyDepartment of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Viale Ferdinando Stagno D’Alcontres 31, 98166 Messina, ItalyDepartment of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Viale Ferdinando Stagno D’Alcontres 31, 98166 Messina, ItalyDepartment of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Viale Ferdinando Stagno D’Alcontres 31, 98166 Messina, ItalyDepartment of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Viale Ferdinando Stagno D’Alcontres 31, 98166 Messina, ItalyDistillation is the most widely used method to obtain an essential oil from plant material. The biomass used in the process is returned as a solid residue together with variable amounts of water rich in water-soluble compounds, which currently are not addressed to any further application. The scope of this work was to evaluate the phytochemical composition of wastewaters coming from hydrodistillation (DWWs) of five aromatic plants belonging to the <i>Lamiaceae</i> family, and to assess their in vitro antioxidant and anti-inflammatory activities. The phenolic profiles of the DWWs were determined by HPLC-DAD and HPLC-ESI/MS. Free radical scavenging ability, oxygen radical antioxidant capacity and superoxide dismutase mimetic activity of the samples under study were measured. Moreover, to investigate the anti-inflammatory activity of the DWWs, an in vitro experimental model of intestinal inflammation was used. The DWW samples’ phytochemical analysis allowed the identification of 37 phenolic compounds, all exhibiting good antioxidant and anti-inflammatory activity. Our study contributes to the knowledge on the polyphenolic composition of the DWWs of five aromatic plants of the Lamiaceae family. The results highlight the presence of compounds with proven biological activity, and therefore of great interest in the pharmaceutical and nutraceutical fields.https://www.mdpi.com/1420-3049/27/21/7427distillation wastesphenolic profilerosmarinic acidintestinal inflammationanti-inflammatoryradical scavenging |
| spellingShingle | Edoardo Napoli Giuseppe Ruberto Alessandra Carrubba Mauro Sarno Claudia Muscarà Antonio Speciale Mariateresa Cristani Francesco Cimino Antonella Saija Phenolic Profiles, Antioxidant and Anti-Inflammatory Activities of Hydrodistillation Wastewaters from Five Lamiaceae Species Molecules distillation wastes phenolic profile rosmarinic acid intestinal inflammation anti-inflammatory radical scavenging |
| title | Phenolic Profiles, Antioxidant and Anti-Inflammatory Activities of Hydrodistillation Wastewaters from Five Lamiaceae Species |
| title_full | Phenolic Profiles, Antioxidant and Anti-Inflammatory Activities of Hydrodistillation Wastewaters from Five Lamiaceae Species |
| title_fullStr | Phenolic Profiles, Antioxidant and Anti-Inflammatory Activities of Hydrodistillation Wastewaters from Five Lamiaceae Species |
| title_full_unstemmed | Phenolic Profiles, Antioxidant and Anti-Inflammatory Activities of Hydrodistillation Wastewaters from Five Lamiaceae Species |
| title_short | Phenolic Profiles, Antioxidant and Anti-Inflammatory Activities of Hydrodistillation Wastewaters from Five Lamiaceae Species |
| title_sort | phenolic profiles antioxidant and anti inflammatory activities of hydrodistillation wastewaters from five lamiaceae species |
| topic | distillation wastes phenolic profile rosmarinic acid intestinal inflammation anti-inflammatory radical scavenging |
| url | https://www.mdpi.com/1420-3049/27/21/7427 |
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