Tumor Suppressors Having Oncogenic Functions: The Double Agents
Cancer progression involves multiple genetic and epigenetic events, which involve gain-of-functions of oncogenes and loss-of-functions of tumor suppressor genes. Classical tumor suppressor genes are recessive in nature, anti-proliferative, and frequently found inactivated or mutated in cancers. Howe...
Main Authors: | Neerajana Datta, Shrabastee Chakraborty, Malini Basu, Mrinal K. Ghosh |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-12-01
|
Series: | Cells |
Subjects: | |
Online Access: | https://www.mdpi.com/2073-4409/10/1/46 |
Similar Items
-
Retinoblastoma tumor suppressor gene: An overview
by: Sunila Thomas, et al.
Published: (2012-01-01) -
The Novel Phosphatase Domain Mutations Q171R and Y65S Switch PTEN from Tumor Suppressor to Oncogene
by: Jose Antonio Ma. G. Garrido, et al.
Published: (2021-12-01) -
Is PML a tumor suppressor?
by: Massimiliano eMazza, et al.
Published: (2013-07-01) -
VAV Proteins as Double Agents in Cancer: Oncogenes with Tumor Suppressor Roles
by: Myriam Cuadrado, et al.
Published: (2021-09-01) -
Cyclin D activates the Rb tumor suppressor by mono-phosphorylation
by: Anil M Narasimha, et al.
Published: (2014-05-01)