The Impact of COVID-19 Pandemic on ESBL-Producing <i>Enterobacterales</i> Infections: A Scoping Review
Several studies have reported an increased frequency of colonization and/or infection with antibiotic-resistant bacteria (ARB) during the COVID-19 pandemic. Extended-spectrum beta-lactamase-producing <i>Enterobacterales</i> (ESBL-PE) are a group of bacteria with intrinsic resistance to m...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-06-01
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| Series: | Antibiotics |
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| Online Access: | https://www.mdpi.com/2079-6382/12/6/1064 |
| _version_ | 1827738929261969408 |
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| author | Ha Thi Thao Mai J. Luis Espinoza |
| author_facet | Ha Thi Thao Mai J. Luis Espinoza |
| author_sort | Ha Thi Thao Mai |
| collection | DOAJ |
| description | Several studies have reported an increased frequency of colonization and/or infection with antibiotic-resistant bacteria (ARB) during the COVID-19 pandemic. Extended-spectrum beta-lactamase-producing <i>Enterobacterales</i> (ESBL-PE) are a group of bacteria with intrinsic resistance to multiple antibiotics, including penicillins, cephalosporins, and monobactams. These pathogens are easy to spread and can cause difficult-to-treat infections. Here, we summarize the available evidence on the impact of the COVID-19 pandemic on infections caused by ESBL-PE. Using specific criteria and keywords, we searched PubMed, MEDLINE, and EMBASE for articles published up to 30 March 2023 on potential changes in the epidemiology of ESBL-E since the beginning of the COVID-19 pandemic. We identified eight studies that documented the impact of COVID-19 on ESBL-E. Five studies were focused on assessing the frequency of ESBL-PE in patient-derived specimens, and three studies investigated the epidemiological aspects of ESBL-PE infections in the context of the COVID-19 pandemic. Some of the studies that were focused on patient specimens reported a decrease in ESBL-PE positivity during the pandemic, whereas the three studies that involved patient data (1829 patients in total) reported a higher incidence of ESBL-PE infections in patients hospitalized for COVID-19 compared with those with other conditions. There are limited data on the real impact of the COVID-19 pandemic on the epidemiology of ESBL-PE infections; however, patient-derived data suggest that the pandemic has exacerbated the spread of these pathogens. |
| first_indexed | 2024-03-11T02:51:01Z |
| format | Article |
| id | doaj.art-b7a9d2ec277b42da9e8f0dfcd1d4d544 |
| institution | Directory Open Access Journal |
| issn | 2079-6382 |
| language | English |
| last_indexed | 2024-03-11T02:51:01Z |
| publishDate | 2023-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Antibiotics |
| spelling | doaj.art-b7a9d2ec277b42da9e8f0dfcd1d4d5442023-11-18T09:01:32ZengMDPI AGAntibiotics2079-63822023-06-01126106410.3390/antibiotics12061064The Impact of COVID-19 Pandemic on ESBL-Producing <i>Enterobacterales</i> Infections: A Scoping ReviewHa Thi Thao Mai0J. Luis Espinoza1Department of Biochemistry, Faculty of Medicine, Can Tho University of Medicine and Pharmacy, Can Tho City 900000, VietnamFaculty of Health Sciences, Kanazawa University, Kanazawa 920-0942, Ishikawa, JapanSeveral studies have reported an increased frequency of colonization and/or infection with antibiotic-resistant bacteria (ARB) during the COVID-19 pandemic. Extended-spectrum beta-lactamase-producing <i>Enterobacterales</i> (ESBL-PE) are a group of bacteria with intrinsic resistance to multiple antibiotics, including penicillins, cephalosporins, and monobactams. These pathogens are easy to spread and can cause difficult-to-treat infections. Here, we summarize the available evidence on the impact of the COVID-19 pandemic on infections caused by ESBL-PE. Using specific criteria and keywords, we searched PubMed, MEDLINE, and EMBASE for articles published up to 30 March 2023 on potential changes in the epidemiology of ESBL-E since the beginning of the COVID-19 pandemic. We identified eight studies that documented the impact of COVID-19 on ESBL-E. Five studies were focused on assessing the frequency of ESBL-PE in patient-derived specimens, and three studies investigated the epidemiological aspects of ESBL-PE infections in the context of the COVID-19 pandemic. Some of the studies that were focused on patient specimens reported a decrease in ESBL-PE positivity during the pandemic, whereas the three studies that involved patient data (1829 patients in total) reported a higher incidence of ESBL-PE infections in patients hospitalized for COVID-19 compared with those with other conditions. There are limited data on the real impact of the COVID-19 pandemic on the epidemiology of ESBL-PE infections; however, patient-derived data suggest that the pandemic has exacerbated the spread of these pathogens.https://www.mdpi.com/2079-6382/12/6/1064antibiotic-resistant bacteriamultidrug-resistant organisms<i>Enterobacterales</i> extended-spectrum β-lactamase-producing <i>Enterobacterales</i> |
| spellingShingle | Ha Thi Thao Mai J. Luis Espinoza The Impact of COVID-19 Pandemic on ESBL-Producing <i>Enterobacterales</i> Infections: A Scoping Review Antibiotics antibiotic-resistant bacteria multidrug-resistant organisms <i>Enterobacterales</i> extended-spectrum β-lactamase-producing <i>Enterobacterales</i> |
| title | The Impact of COVID-19 Pandemic on ESBL-Producing <i>Enterobacterales</i> Infections: A Scoping Review |
| title_full | The Impact of COVID-19 Pandemic on ESBL-Producing <i>Enterobacterales</i> Infections: A Scoping Review |
| title_fullStr | The Impact of COVID-19 Pandemic on ESBL-Producing <i>Enterobacterales</i> Infections: A Scoping Review |
| title_full_unstemmed | The Impact of COVID-19 Pandemic on ESBL-Producing <i>Enterobacterales</i> Infections: A Scoping Review |
| title_short | The Impact of COVID-19 Pandemic on ESBL-Producing <i>Enterobacterales</i> Infections: A Scoping Review |
| title_sort | impact of covid 19 pandemic on esbl producing i enterobacterales i infections a scoping review |
| topic | antibiotic-resistant bacteria multidrug-resistant organisms <i>Enterobacterales</i> extended-spectrum β-lactamase-producing <i>Enterobacterales</i> |
| url | https://www.mdpi.com/2079-6382/12/6/1064 |
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