ORIGINAL PAPER: <br> The association of 25-hydroxyvitamin D levels with secondary hyperparathyroidism in end-stage renal failure patients undergoing regular hemodialysis
Introduction: To investigate the role of 25-OHD as a marker of nutrition and its association with mineral metabolism and serum parathormone secretion in end-stage renal failure patients undergoing regular hemodialysis (HD), a cross sectional study was carried out on a group of maintenance hemodialys...
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| Format: | Article |
| Language: | English |
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Termedia Publishing House
2005-12-01
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| Series: | Archives of Medical Science |
| Subjects: | |
| Online Access: | http://www.termedia.pl/magazine.php?magazine_id=19&article_id=4202&magazine_subpage=FULL_TEXT |
| _version_ | 1811246392320983040 |
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| author | Azar Baradaran Hamid Nasri |
| author_facet | Azar Baradaran Hamid Nasri |
| author_sort | Azar Baradaran |
| collection | DOAJ |
| description | Introduction: To investigate the role of 25-OHD as a marker of nutrition and its association with mineral metabolism and serum parathormone secretion in end-stage renal failure patients undergoing regular hemodialysis (HD), a cross sectional study was carried out on a group of maintenance hemodialysis patients. Material and methods: Serum 25-hydroxy (25-OH vitamin D) levels, Intact serum PTH (iPTH) and also serum C-reactive protein(CRP), calcium, phosphorus and alkaline phosphatase (ALP) were measured. Results: In the study, significant differences of serum 25-OH vitamin D between diabetic and non-diabetics of male dialysis patients with more values in nondiabetic HD patients and a significant positive correlation of serum 25-OH vitamin D with BMI and also a near significant inverse correlation of serum 25-OH vitamin D with serum phosphorus were found, also a significant inverse correlation of serum 25-OH VitD with serum calcium was seen, too. Moreover, a weakly significant inverse correlation of serum 25-OH vitamin D with serum iPTH was seen, too. In this study no significant association between serum 25-OH vitamin D with serum albumin, CRP, ALP, dialysis adequacy and ages of the patients, duration and sessions of dialysis were found. Conclusions: In hemodialysis patients, low serum 25-OHD levels could be a risk factor for secondary hyperparathyroidism. Serum 25-OHD could show the nutritional status of HD patients. In dialysis patients, we suggest that the plasma levels of 25-OHD are maintained around the upper limit of the reference range of sunny countries. |
| first_indexed | 2024-04-12T14:52:46Z |
| format | Article |
| id | doaj.art-b7ad6bcf59574c049fa2e8a03b1a5020 |
| institution | Directory Open Access Journal |
| issn | 1734-1922 |
| language | English |
| last_indexed | 2024-04-12T14:52:46Z |
| publishDate | 2005-12-01 |
| publisher | Termedia Publishing House |
| record_format | Article |
| series | Archives of Medical Science |
| spelling | doaj.art-b7ad6bcf59574c049fa2e8a03b1a50202022-12-22T03:28:22ZengTermedia Publishing HouseArchives of Medical Science1734-19222005-12-014236240ORIGINAL PAPER: <br> The association of 25-hydroxyvitamin D levels with secondary hyperparathyroidism in end-stage renal failure patients undergoing regular hemodialysisAzar BaradaranHamid NasriIntroduction: To investigate the role of 25-OHD as a marker of nutrition and its association with mineral metabolism and serum parathormone secretion in end-stage renal failure patients undergoing regular hemodialysis (HD), a cross sectional study was carried out on a group of maintenance hemodialysis patients. Material and methods: Serum 25-hydroxy (25-OH vitamin D) levels, Intact serum PTH (iPTH) and also serum C-reactive protein(CRP), calcium, phosphorus and alkaline phosphatase (ALP) were measured. Results: In the study, significant differences of serum 25-OH vitamin D between diabetic and non-diabetics of male dialysis patients with more values in nondiabetic HD patients and a significant positive correlation of serum 25-OH vitamin D with BMI and also a near significant inverse correlation of serum 25-OH vitamin D with serum phosphorus were found, also a significant inverse correlation of serum 25-OH VitD with serum calcium was seen, too. Moreover, a weakly significant inverse correlation of serum 25-OH vitamin D with serum iPTH was seen, too. In this study no significant association between serum 25-OH vitamin D with serum albumin, CRP, ALP, dialysis adequacy and ages of the patients, duration and sessions of dialysis were found. Conclusions: In hemodialysis patients, low serum 25-OHD levels could be a risk factor for secondary hyperparathyroidism. Serum 25-OHD could show the nutritional status of HD patients. In dialysis patients, we suggest that the plasma levels of 25-OHD are maintained around the upper limit of the reference range of sunny countries.http://www.termedia.pl/magazine.php?magazine_id=19&article_id=4202&magazine_subpage=FULL_TEXT25-hydroxy vitamin Dend-stage renal failuresecondary hyperparathyroidismnutritional statusregular hemodialysisparathormone |
| spellingShingle | Azar Baradaran Hamid Nasri ORIGINAL PAPER: <br> The association of 25-hydroxyvitamin D levels with secondary hyperparathyroidism in end-stage renal failure patients undergoing regular hemodialysis Archives of Medical Science 25-hydroxy vitamin D end-stage renal failure secondary hyperparathyroidism nutritional status regular hemodialysis parathormone |
| title | ORIGINAL PAPER: <br> The association of 25-hydroxyvitamin D levels with secondary hyperparathyroidism in end-stage renal failure patients undergoing regular hemodialysis |
| title_full | ORIGINAL PAPER: <br> The association of 25-hydroxyvitamin D levels with secondary hyperparathyroidism in end-stage renal failure patients undergoing regular hemodialysis |
| title_fullStr | ORIGINAL PAPER: <br> The association of 25-hydroxyvitamin D levels with secondary hyperparathyroidism in end-stage renal failure patients undergoing regular hemodialysis |
| title_full_unstemmed | ORIGINAL PAPER: <br> The association of 25-hydroxyvitamin D levels with secondary hyperparathyroidism in end-stage renal failure patients undergoing regular hemodialysis |
| title_short | ORIGINAL PAPER: <br> The association of 25-hydroxyvitamin D levels with secondary hyperparathyroidism in end-stage renal failure patients undergoing regular hemodialysis |
| title_sort | original paper br the association of 25 hydroxyvitamin d levels with secondary hyperparathyroidism in end stage renal failure patients undergoing regular hemodialysis |
| topic | 25-hydroxy vitamin D end-stage renal failure secondary hyperparathyroidism nutritional status regular hemodialysis parathormone |
| url | http://www.termedia.pl/magazine.php?magazine_id=19&article_id=4202&magazine_subpage=FULL_TEXT |
| work_keys_str_mv | AT azarbaradaran originalpaperbrtheassociationof25hydroxyvitamindlevelswithsecondaryhyperparathyroidisminendstagerenalfailurepatientsundergoingregularhemodialysis AT hamidnasri originalpaperbrtheassociationof25hydroxyvitamindlevelswithsecondaryhyperparathyroidisminendstagerenalfailurepatientsundergoingregularhemodialysis |