Generation of a TPM1 homozygous knockout embryonic stem cell line by CRISPR/Cas9 editing

Generation of a TPM1 homozygous knockout embryonic stem cell line by CRISPR/Cas9 editing

Alpha-Tropomyosin (TPM1) plays a crucial role in actin regulation and stability and contributes fundamental functions to heart development: without TPM1 expressing, mice embryos will die early in embryogenesis. To further identify the role of TPM1 in human cardiac development, here we generated a ho...

Bibliográfalaš dieđut
Váldodahkkit:	Shuhong Ma, Qi Xu, Rui Bai, Tao Dong, Zhiping Peng, Xujie Liu
Materiálatiipa:	Artihkal
Giella:	English
Almmustuhtton:	Elsevier 2021-08-01
Ráidu:	Stem Cell Research
Liŋkkat:	http://www.sciencedirect.com/science/article/pii/S1873506121003172

Geahča maid

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The establishment of a homozygous SNTA1 knockout human embryonic stem cell line (WAe009-A-50) using the CRISPR/Cas9 system
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Generation of a TSC2 knockout embryonic stem cell line by CRISPR/Cas9 editing
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Generation of a homozygous S100A1 knockout human embryonic stem cell line (WAe009-A-73) by the CRISPR/Cas9 editing system
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Generation of a FTO gene knockout human embryonic stem cell line using CRISPR/Cas9 editing
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Generation of a homozygous GRIN2A gene knockout human embryonic stem cell line using CRISPR/Cas9 system
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Generation of a homozygous FIS1 knockout human embryonic stem cell line GIBHe015-B by CRISPR/Cas9 system
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Generation of a Junctophilin-2 homozygous knockout human embryonic stem cell line (WAe009-A-36) by an episomal vector-based CRISPR/Cas9 system
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Corrigendum to “Generation of two RNF2 homozygous knockout human embryonic stem cell lines by CRISPR/Cas9 system” [Stem Cell Res. 47 (2020) 101885]
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