Role of HNF6 in liver homeostasis and pathophysiology

Role of HNF6 in liver homeostasis and pathophysiology

Abstract Background Hepatocyte nuclear factor 6 (HNF6), a member of the HNF family, contains single cleft and homologous domains, which form a DNA-binding region that targets the promoter regions of genes that bind to liver-specific genes and regulate their expression. Furthermore, HNF6 is highly ex...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Miaomiao Tian, Weizhen Gao, Shujun Ma, Huiling Cao, Yu Zhang, Fuxiang An, Jianni Qi, Zhen Yang
Format: Artikel
Sprache:English
Veröffentlicht: BMC 2025-02-01
Schriftenreihe:Molecular Medicine
Schlagworte:
HNF6
Epigenetic modifications
Metabolism
Liver pathophysiology
Transcription factor
Online Zugang:https://doi.org/10.1186/s10020-025-01105-9

Online

https://doi.org/10.1186/s10020-025-01105-9

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