Disseminated cerebral thrombotic microangiopathy in a patient with adult's Still disease
OBJECTIVE: The aim of this report is to describe a fatal disseminated thrombotic micoangiopathy with renal, pancreatic, and cerebral involvement in a patient with recently diagnosed adult's Still disease (ASD). CASE REPORT: A previously healthy 15 year old girl was admitted to our hospital. Acc...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Academia Brasileira de Neurologia (ABNEURO)
2003-06-01
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| Series: | Arquivos de Neuro-Psiquiatria |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2003000200018&tlng=en |
| _version_ | 1798021451999084544 |
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| author | Renan B. Domingues Ana Maria Casati da Gama Eliana B. Caser Carlos Musso Maria Carmen S. Santos |
| author_facet | Renan B. Domingues Ana Maria Casati da Gama Eliana B. Caser Carlos Musso Maria Carmen S. Santos |
| author_sort | Renan B. Domingues |
| collection | DOAJ |
| description | OBJECTIVE: The aim of this report is to describe a fatal disseminated thrombotic micoangiopathy with renal, pancreatic, and cerebral involvement in a patient with recently diagnosed adult's Still disease (ASD). CASE REPORT: A previously healthy 15 year old girl was admitted to our hospital. According to the clinical and laboratory data the diagnosis of adult's still Disease was established. The treatment was begun and few days after an initial improvement a sudden neurologic deterioration with coma and seizures has occurred. Hours later the patient died. Clinical, laboratorial, and pathologic data will be presented. CONCLUSION: To our knowledge this is the second description of a fatal disseminated cerebral thrombotic microangiopathy in a patient with adult's Still disease, but with a much more fulminating evolution than previously reported. Some etiopathogenic mechanisms could be shared in these two disorders explaining this coexistence. |
| first_indexed | 2024-04-11T17:13:57Z |
| format | Article |
| id | doaj.art-b7b8198eebfb4752ac40286fabb2f91d |
| institution | Directory Open Access Journal |
| issn | 1678-4227 |
| language | English |
| last_indexed | 2024-04-11T17:13:57Z |
| publishDate | 2003-06-01 |
| publisher | Academia Brasileira de Neurologia (ABNEURO) |
| record_format | Article |
| series | Arquivos de Neuro-Psiquiatria |
| spelling | doaj.art-b7b8198eebfb4752ac40286fabb2f91d2022-12-22T04:12:45ZengAcademia Brasileira de Neurologia (ABNEURO)Arquivos de Neuro-Psiquiatria1678-42272003-06-01612A25926110.1590/S0004-282X2003000200018Disseminated cerebral thrombotic microangiopathy in a patient with adult's Still diseaseRenan B. Domingues0Ana Maria Casati da Gama1Eliana B. Caser2Carlos Musso3Maria Carmen S. Santos4Santa Casa de Misericórdia de VitóriaUniversidade Federal do Espírito SantoUniversidade Federal do Espírito SantoUniversidade Federal do Espírito SantoUniversidade Federal do Espírito SantoOBJECTIVE: The aim of this report is to describe a fatal disseminated thrombotic micoangiopathy with renal, pancreatic, and cerebral involvement in a patient with recently diagnosed adult's Still disease (ASD). CASE REPORT: A previously healthy 15 year old girl was admitted to our hospital. According to the clinical and laboratory data the diagnosis of adult's still Disease was established. The treatment was begun and few days after an initial improvement a sudden neurologic deterioration with coma and seizures has occurred. Hours later the patient died. Clinical, laboratorial, and pathologic data will be presented. CONCLUSION: To our knowledge this is the second description of a fatal disseminated cerebral thrombotic microangiopathy in a patient with adult's Still disease, but with a much more fulminating evolution than previously reported. Some etiopathogenic mechanisms could be shared in these two disorders explaining this coexistence.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2003000200018&tlng=enadult's Still diseasecerebral thrombotic microangiopathythrombotic thrombocitopenic purpura |
| spellingShingle | Renan B. Domingues Ana Maria Casati da Gama Eliana B. Caser Carlos Musso Maria Carmen S. Santos Disseminated cerebral thrombotic microangiopathy in a patient with adult's Still disease Arquivos de Neuro-Psiquiatria adult's Still disease cerebral thrombotic microangiopathy thrombotic thrombocitopenic purpura |
| title | Disseminated cerebral thrombotic microangiopathy in a patient with adult's Still disease |
| title_full | Disseminated cerebral thrombotic microangiopathy in a patient with adult's Still disease |
| title_fullStr | Disseminated cerebral thrombotic microangiopathy in a patient with adult's Still disease |
| title_full_unstemmed | Disseminated cerebral thrombotic microangiopathy in a patient with adult's Still disease |
| title_short | Disseminated cerebral thrombotic microangiopathy in a patient with adult's Still disease |
| title_sort | disseminated cerebral thrombotic microangiopathy in a patient with adult s still disease |
| topic | adult's Still disease cerebral thrombotic microangiopathy thrombotic thrombocitopenic purpura |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2003000200018&tlng=en |
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