Osteocalcin activates lipophagy via the ADPN-AMPK/PPARα-mTOR signaling pathway in chicken embryonic hepatocyte

Osteocalcin activates lipophagy via the ADPN-AMPK/PPARα-mTOR signaling pathway in chicken embryonic hepatocyte

ABSTRACT: Fatty liver hemorrhage syndrome (FLHS) is the leading cause of noninfectious mortality in caged layers worldwide. Osteocalcin (OCN) is a protein secreted by osteoblasts, and its undercarboxylated form (ucOCN) acts as a multifunctional hormone that protects laying hens from FLHS. Lipophagy...

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Bibliographic Details
Main Authors: W.J. Tu, Y.H. Zhang, X.T. Wang, M. Zhang, K.Y. Jiang, S. Jiang
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:Poultry Science
Subjects:
osteocalcin
fatty liver hemorrhagic syndrome
chicken embryonic hepatocyte
ADPN/AMPK/mTOR
lipophagy
Online Access:http://www.sciencedirect.com/science/article/pii/S003257912300812X

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