Upregulation of RSPO3 via targeted promoter DNA demethylation inhibits the progression of cholangiocarcinoma

Upregulation of RSPO3 via targeted promoter DNA demethylation inhibits the progression of cholangiocarcinoma

Abstract Background Cholangiocarcinoma (CCA) refers to a collection of malignant tumors that develop from the biliary epithelium. Extensive clinical evidence and epidemiological observations indicate a concerning increase in both the incidence and mortality rates of CCA. Surgical resection is curren...

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Bibliographic Details
Main Authors: Guanhua Wu, Da Wang, Fei Xiong, Wenzheng Liu, Qi Wang, Junsheng Chen, Bing Wang, Yongjun Chen
Format: Article
Language:English
Published: BMC 2023-11-01
Series:Clinical Epigenetics
Subjects:
RSPO3
DNA methylation
TET1
Targeted demethylation
Precise treatment
Online Access:https://doi.org/10.1186/s13148-023-01592-9

Internet

https://doi.org/10.1186/s13148-023-01592-9

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