Pharmaceutical Pollution and Disposal of Expired, Unused, and Unwanted Medicines in the Brazilian Context

The occurrence of pharmaceuticals in the environment is an everyday recognized concern worldwide, and drugs as environmental contaminants have been detected in water and soil systems, posing risks to humans and wildlife. The presence of drugs in wastewater, groundwater, and even drinking water occur...

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Main Authors: Letícia de Araújo Almeida Freitas, Gandhi Radis-Baptista
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Journal of Xenobiotics
Subjects:
Online Access:https://www.mdpi.com/2039-4713/11/2/5
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author Letícia de Araújo Almeida Freitas
Gandhi Radis-Baptista
author_facet Letícia de Araújo Almeida Freitas
Gandhi Radis-Baptista
author_sort Letícia de Araújo Almeida Freitas
collection DOAJ
description The occurrence of pharmaceuticals in the environment is an everyday recognized concern worldwide, and drugs as environmental contaminants have been detected in water and soil systems, posing risks to humans and wildlife. The presence of drugs in wastewater, groundwater, and even drinking water occurs in several countries, including Brazil, where the pharmaceutical market is expanding over the years. The adverse, harmful effects of pharmaceuticals in the environment range from the spreading of antimicrobial resistance and species survival to the interference with reproduction and increased cancer incidence in humans. Therefore, it is demanding to count on proper legislation to prevent these pollutants from entering the distinct environment compartments. In some developed countries, laws, directives, programs, and initiatives regarding drug disposal reach a mature status. In Brazil, federal laws dealing with drug residues’ management are recent, with flaws that might facilitate non-compliance with drug pollution issues. Besides, pharmacies and drugstores are not obligated to collect unneeded household medicines, while particular State laws aim to ordinate the disposal of drug residues regionally. In this review, we consider the current knowledge about pharmaceutical (drug) pollution, the recommendation and regulations on the disposal of useless medicines in some countries, and in the context of the expanding pharmaceutical market in Brazil. The awareness of emerging contaminants in the environment, besides the joint effort of authorities, consumers, and the general public nationwide, will be required to avoid pharmaceutical/drug pollution and achieve an eco-friendly environment and a sustainable society.
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spelling doaj.art-b7bfc69d770d4050a0ad0e113e7e87c12023-11-21T22:21:25ZengMDPI AGJournal of Xenobiotics2039-47052039-47132021-05-01112617610.3390/jox11020005Pharmaceutical Pollution and Disposal of Expired, Unused, and Unwanted Medicines in the Brazilian ContextLetícia de Araújo Almeida Freitas0Gandhi Radis-Baptista1Post-Graduate Program in Pharmaceutical Sciences, School of Pharmacy, Dentistry and Nursing, Federal University of Ceará, Fortaleza, CE 60416-030, BrazilPost-Graduate Program in Pharmaceutical Sciences, School of Pharmacy, Dentistry and Nursing, Federal University of Ceará, Fortaleza, CE 60416-030, BrazilThe occurrence of pharmaceuticals in the environment is an everyday recognized concern worldwide, and drugs as environmental contaminants have been detected in water and soil systems, posing risks to humans and wildlife. The presence of drugs in wastewater, groundwater, and even drinking water occurs in several countries, including Brazil, where the pharmaceutical market is expanding over the years. The adverse, harmful effects of pharmaceuticals in the environment range from the spreading of antimicrobial resistance and species survival to the interference with reproduction and increased cancer incidence in humans. Therefore, it is demanding to count on proper legislation to prevent these pollutants from entering the distinct environment compartments. In some developed countries, laws, directives, programs, and initiatives regarding drug disposal reach a mature status. In Brazil, federal laws dealing with drug residues’ management are recent, with flaws that might facilitate non-compliance with drug pollution issues. Besides, pharmacies and drugstores are not obligated to collect unneeded household medicines, while particular State laws aim to ordinate the disposal of drug residues regionally. In this review, we consider the current knowledge about pharmaceutical (drug) pollution, the recommendation and regulations on the disposal of useless medicines in some countries, and in the context of the expanding pharmaceutical market in Brazil. The awareness of emerging contaminants in the environment, besides the joint effort of authorities, consumers, and the general public nationwide, will be required to avoid pharmaceutical/drug pollution and achieve an eco-friendly environment and a sustainable society.https://www.mdpi.com/2039-4713/11/2/5pharmaceutical pollutiondrug pollutionactive pharmaceutical ingredientsenvironmental pollutionhazardous wastedrug disposal
spellingShingle Letícia de Araújo Almeida Freitas
Gandhi Radis-Baptista
Pharmaceutical Pollution and Disposal of Expired, Unused, and Unwanted Medicines in the Brazilian Context
Journal of Xenobiotics
pharmaceutical pollution
drug pollution
active pharmaceutical ingredients
environmental pollution
hazardous waste
drug disposal
title Pharmaceutical Pollution and Disposal of Expired, Unused, and Unwanted Medicines in the Brazilian Context
title_full Pharmaceutical Pollution and Disposal of Expired, Unused, and Unwanted Medicines in the Brazilian Context
title_fullStr Pharmaceutical Pollution and Disposal of Expired, Unused, and Unwanted Medicines in the Brazilian Context
title_full_unstemmed Pharmaceutical Pollution and Disposal of Expired, Unused, and Unwanted Medicines in the Brazilian Context
title_short Pharmaceutical Pollution and Disposal of Expired, Unused, and Unwanted Medicines in the Brazilian Context
title_sort pharmaceutical pollution and disposal of expired unused and unwanted medicines in the brazilian context
topic pharmaceutical pollution
drug pollution
active pharmaceutical ingredients
environmental pollution
hazardous waste
drug disposal
url https://www.mdpi.com/2039-4713/11/2/5
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