Combretastatins D series and analogues: from isolation, synthetic challenges and biological activities
The combretastatin D series and its analogues, corniculatolides and isocorniculatolides belong to a class of macrocycles called cyclic diaryl ether heptanoids (DAEH). This review is intended to highlight the structure elucidation, biosynthesis, and biological activity of these compounds as well as t...
Main Authors: | , |
---|---|
Format: | Article |
Language: | English |
Published: |
Beilstein-Institut
2023-03-01
|
Series: | Beilstein Journal of Organic Chemistry |
Subjects: | |
Online Access: | https://doi.org/10.3762/bjoc.19.31 |
_version_ | 1827973371872149504 |
---|---|
author | Jorge de Lima Neto Paulo Henrique Menezes |
author_facet | Jorge de Lima Neto Paulo Henrique Menezes |
author_sort | Jorge de Lima Neto |
collection | DOAJ |
description | The combretastatin D series and its analogues, corniculatolides and isocorniculatolides belong to a class of macrocycles called cyclic diaryl ether heptanoids (DAEH). This review is intended to highlight the structure elucidation, biosynthesis, and biological activity of these compounds as well as the use of different strategies for their synthesis. |
first_indexed | 2024-04-09T19:34:52Z |
format | Article |
id | doaj.art-b7c1d2ad45a84e9e9a92df0a77b2a594 |
institution | Directory Open Access Journal |
issn | 1860-5397 |
language | English |
last_indexed | 2024-04-09T19:34:52Z |
publishDate | 2023-03-01 |
publisher | Beilstein-Institut |
record_format | Article |
series | Beilstein Journal of Organic Chemistry |
spelling | doaj.art-b7c1d2ad45a84e9e9a92df0a77b2a5942023-04-04T13:41:08ZengBeilstein-InstitutBeilstein Journal of Organic Chemistry1860-53972023-03-0119139942710.3762/bjoc.19.311860-5397-19-31Combretastatins D series and analogues: from isolation, synthetic challenges and biological activitiesJorge de Lima Neto0Paulo Henrique Menezes1Universidade Federal de Pernambuco, Departamento de Química Fundamental, Recife-PE, 50740-560, Brazil Universidade Federal de Pernambuco, Departamento de Química Fundamental, Recife-PE, 50740-560, Brazil The combretastatin D series and its analogues, corniculatolides and isocorniculatolides belong to a class of macrocycles called cyclic diaryl ether heptanoids (DAEH). This review is intended to highlight the structure elucidation, biosynthesis, and biological activity of these compounds as well as the use of different strategies for their synthesis.https://doi.org/10.3762/bjoc.19.31combretastatin dcorniculatolideisocorniculatolidemacrocycles |
spellingShingle | Jorge de Lima Neto Paulo Henrique Menezes Combretastatins D series and analogues: from isolation, synthetic challenges and biological activities Beilstein Journal of Organic Chemistry combretastatin d corniculatolide isocorniculatolide macrocycles |
title | Combretastatins D series and analogues: from isolation, synthetic challenges and biological activities |
title_full | Combretastatins D series and analogues: from isolation, synthetic challenges and biological activities |
title_fullStr | Combretastatins D series and analogues: from isolation, synthetic challenges and biological activities |
title_full_unstemmed | Combretastatins D series and analogues: from isolation, synthetic challenges and biological activities |
title_short | Combretastatins D series and analogues: from isolation, synthetic challenges and biological activities |
title_sort | combretastatins d series and analogues from isolation synthetic challenges and biological activities |
topic | combretastatin d corniculatolide isocorniculatolide macrocycles |
url | https://doi.org/10.3762/bjoc.19.31 |
work_keys_str_mv | AT jorgedelimaneto combretastatinsdseriesandanaloguesfromisolationsyntheticchallengesandbiologicalactivities AT paulohenriquemenezes combretastatinsdseriesandanaloguesfromisolationsyntheticchallengesandbiologicalactivities |