Atypical Bacteria and Macrolides in Asthma
<p/> <p><it>Chlamydophila pneumoniae </it>and <it>Mycoplasma pneumoniae </it>are common pathogens causing acute illness in both the upper and lower airways. Several observations are supportive of a possible causative role of these pathogens in asthma; however, mor...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2008-09-01
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| Series: | Allergy, Asthma & Clinical Immunology |
| Subjects: | |
| Online Access: | http://www.aacijournal.com/content/4/3/111 |
| _version_ | 1818540422354436096 |
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| author | Xepapadaki Paraskevi Koutsoumpari Ioanna Papaevagelou Vasiliki Karagianni Christina Papadopoulos Nikolaos G |
| author_facet | Xepapadaki Paraskevi Koutsoumpari Ioanna Papaevagelou Vasiliki Karagianni Christina Papadopoulos Nikolaos G |
| author_sort | Xepapadaki Paraskevi |
| collection | DOAJ |
| description | <p/> <p><it>Chlamydophila pneumoniae </it>and <it>Mycoplasma pneumoniae </it>are common pathogens causing acute illness in both the upper and lower airways. Several observations are supportive of a possible causative role of these pathogens in asthma; however, more evidence is required before this becomes meaningful in clinical practice. Atypical bacteria can enhance airway hyperresponsiveness and inflammation, both of which have been associated with exacerbations in patients with preexisting asthma. It is less clear whether the above mechanisms might also be responsible for the development of asthma. Difficulties in accurately diagnosing these infections contribute to such uncertainty. In the present report, evidence of the involvement of <it>Chlamydophila </it>and <it>Mycoplasma </it>infection in the development and the progression of asthma are reviewed.</p> |
| first_indexed | 2024-12-11T21:55:09Z |
| format | Article |
| id | doaj.art-b7c232766d714839a9cddc99dd41f910 |
| institution | Directory Open Access Journal |
| issn | 1710-1484 1710-1492 |
| language | English |
| last_indexed | 2024-12-11T21:55:09Z |
| publishDate | 2008-09-01 |
| publisher | BMC |
| record_format | Article |
| series | Allergy, Asthma & Clinical Immunology |
| spelling | doaj.art-b7c232766d714839a9cddc99dd41f9102022-12-22T00:49:20ZengBMCAllergy, Asthma & Clinical Immunology1710-14841710-14922008-09-014311111610.1186/1710-1492-4-3-111Atypical Bacteria and Macrolides in AsthmaXepapadaki ParaskeviKoutsoumpari IoannaPapaevagelou VasilikiKaragianni ChristinaPapadopoulos Nikolaos G<p/> <p><it>Chlamydophila pneumoniae </it>and <it>Mycoplasma pneumoniae </it>are common pathogens causing acute illness in both the upper and lower airways. Several observations are supportive of a possible causative role of these pathogens in asthma; however, more evidence is required before this becomes meaningful in clinical practice. Atypical bacteria can enhance airway hyperresponsiveness and inflammation, both of which have been associated with exacerbations in patients with preexisting asthma. It is less clear whether the above mechanisms might also be responsible for the development of asthma. Difficulties in accurately diagnosing these infections contribute to such uncertainty. In the present report, evidence of the involvement of <it>Chlamydophila </it>and <it>Mycoplasma </it>infection in the development and the progression of asthma are reviewed.</p>http://www.aacijournal.com/content/4/3/111asthmaChlamydophila pneumoniaeMycoplasma pneumoniae |
| spellingShingle | Xepapadaki Paraskevi Koutsoumpari Ioanna Papaevagelou Vasiliki Karagianni Christina Papadopoulos Nikolaos G Atypical Bacteria and Macrolides in Asthma Allergy, Asthma & Clinical Immunology asthma Chlamydophila pneumoniae Mycoplasma pneumoniae |
| title | Atypical Bacteria and Macrolides in Asthma |
| title_full | Atypical Bacteria and Macrolides in Asthma |
| title_fullStr | Atypical Bacteria and Macrolides in Asthma |
| title_full_unstemmed | Atypical Bacteria and Macrolides in Asthma |
| title_short | Atypical Bacteria and Macrolides in Asthma |
| title_sort | atypical bacteria and macrolides in asthma |
| topic | asthma Chlamydophila pneumoniae Mycoplasma pneumoniae |
| url | http://www.aacijournal.com/content/4/3/111 |
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